Results 161 to 170 of about 23,764 (211)

Role of Toll-like Receptor/MyD88 Signaling in Lycopene Alleviated Di-2-ethylhexyl Phthalate (DEHP)-Induced Inflammatory Response.

Journal of Agricultural and Food Chemistry, 2022
Lycopene (Lyc) has anti-inflammatory and antioxidant biological functions. Di-2-ethylhexyl phthalate (DEHP) is an extremely harmful and persistent environmental pollutant and is a threat to animal health.
Xueyan Dai, Shi-Yong Zhu, Jian Chen, Mu Li, M. Talukder, Jin-Long Li   +5 more
semanticscholar   +1 more source

Lycopene regulates the mitochondrial unfolded protein response to prevent DEHP-induced cardiac mitochondrial damage in mice.

Food & Function, 2022
Lycopene (LYC), as a kind of carotene, has antioxidant effects. Di(2-ethylhexyl) phthalate (DEHP) was used to improve the flexibility of plastics. However, the potential role of LYC in DEHP induced cardiac injury in mice remains unclear.
J. Cui, Yi Zhao, Hao Zhang, Xue-Nan Li, Jin-Long Li   +4 more
semanticscholar   +1 more source

Phthalate derivative DEHP disturbs the antiproliferative effect of camptothecin in human lung cancer cells by attenuating DNA damage and activating Akt/NF‐κB signaling pathway

Environmental Toxicology, 2022
Plasticizers/phthalates play a facilitating role in the development of cancer and help the tumor to grow and metastasize. Camptothecin (CPT) and its derivatives are known to have anticancer properties of inhibiting cell growth, promoting cell apoptosis ...
Ritesh Urade, C. Chou, Han-Lin Chou, Bing-Hung Chen, Tsu-Nai Wang, E. Tsai, Chun-Tzu Hung, Shyh-Jong Wu, Chien-Chih Chiu   +8 more
semanticscholar   +1 more source

Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study

Vox Sanguinis, 2022
Di(2‐ethylhexyl) phthalate (DEHP) must be removed from blood bag sets in Europe by 27 May 2025. DEHP is known to interact with the red blood cell (RBC) membrane, resulting in reduced haemolysis and thus prolonging shelf‐life.
Anna Razatos, J. Acker, D. de Korte, S. Bégué, F. Noorman, B. Doyle, M. Zia, Kyungyoon Min   +7 more
semanticscholar   +1 more source

Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity.

Food & Function, 2021
Di (2-ethylhexyl) phthalate (DEHP) is a hazardous compound used as a plasticizer in plastic products. As a natural carotenoid, lycopene (LYC) is considered an effective protective agent against various types of organ damage.
Yi Zhao, Jianyun Cui, Hao Zhang, Xue-Nan Li, Mu Li, M. Talukder, Jin-Long Li   +6 more
semanticscholar   +1 more source

Lycopene prevents DEHP-induced testicular endoplasmic reticulum stress via regulating nuclear xenobiotic receptors and unfolded protein response in mice.

Food & Function, 2021
Lycopene (LYC) is a potent antioxidant synthesized by red vegetables or plants. Di-2-ethylhexyl phthalate (DEHP) is frequently detected in diverse agricultural environments and considered as a reproductive toxicant.
Yi Zhao, Ling-Ge Cui, M. Talukder, J. Cui, Hao Zhang, Jin-Long Li   +5 more
semanticscholar   +1 more source

DEHP and toxicity

Journal of Vinyl Technology, 1988
Abstract DEHP has had widespread use in flexible vinyls, serving as the workhorse plasticizer. Extensive studies have shown that DEHP has a very low order of toxicity. Originally, concern developed over the effect DEHP might have on the environment.
Sandra R. Murphy, Brian L. Wadey
openaire   +1 more source

DEHP metabolites in urine of children and DEHP in house dust

International Journal of Hygiene and Environmental Health, 2004
Urine samples from the 2001/2002 pilot study for the German Environmental Survey on children (GerES IV) were analysed for concentrations of the primary DEHP metabolite MEHP (mono(2-ethylhexyl)phthalate) and two secondary DEHP metabolites SOH-MEHP (2-ethyl-5-hydroxy-hexylphthalate) and 5oxo-MEHP (2-ethyl-5-oxo-hexylphthalate).
Kerstin, Becker, Margarete, Seiwert, Jürgen, Angerer, Wolfgang, Heger, Holger M, Koch, Regine, Nagorka, Elke, Rosskamp, Christoph, Schlüter, Bernd, Seifert, Detlef, Ullrich   +9 more
openaire   +2 more sources

Lycopene prevents DEHP-induced liver lipid metabolism disorder by inhibiting HIF-1α-induced PPARα/PPARγ/FXR/LXR system.

Journal of Agricultural and Food Chemistry, 2020
Di-(2-ethylhexyl) phthalate (DEHP) is a widespread pollutant that badly affects animals and human health. Lycopene (LYC) has been used as a dietary supplement that has effective antioxidant and anti-obesity functions.
Yi Zhao, De-Xing Ma, Hong-guang Wang, Mu Li, M. Talukder, Hao-Ran Wang, Jin-Long Li   +6 more
semanticscholar   +1 more source

Aryl Hydrocarbon Receptor as a target for lycopene preventing DEHP-induced spermatogenic disorders.

Journal of Agricultural and Food Chemistry, 2020
Di (2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer to improve its flexibility and workability. Lycopene (LYC) is a natural compound and has promising preventive potentials, especially anti-reproductive toxicity, but specific underlying ...
Yi Zhao, Jia Lin, M. Talukder, Shi-Yong Zhu, Mu Li, Hao-Ran Wang, Jin-Long Li   +6 more
semanticscholar   +1 more source