Results 61 to 70 of about 23,764 (211)

Mono(2‐Ethylhexyl) Phthalate Induces Inflammatory and Angiogenic Alterations Mediated by the PI3K/AKT Pathway in HTR‐8/SVneo Trophoblastic Cells

Environmental Toxicology, EarlyView.
ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo, Ericka Karol Pamela Almeida‐Aguirre, Mariana Bobadilla‐Bravo, Ismael Mancilla‐Herrera, Alejandra Martínez‐Ibarra, Marco Cerbón   +5 more
wiley   +1 more source

Trouble in Toyland: The 23rd Annual Toy Safety Survey [PDF]

, 2008
Details findings on deaths and injuries from and toxic chemicals in toys, with a focus on lead and phthalates. Includes tips for consumers and recommendations for policy makers and the Consumer Product Safety Commission.
Edmund Mierzwinski, Liz Hitchcock
core  

Association of Exposure to Phthalates with Endometriosis and Uterine Leiomyomata: Findings from NHANES, 1999-2004 [PDF]

, 2010
BACKGROUND. Phthalates are ubiquitous chemicals used in consumer products. Some phthalates are reproductive toxicants in experimental animals, but human data are limited. OBJECTIVE.
Andersen J, Antonia M. Calafat, Attia GR, Breslow NE, CDC (Centers for Disease Control and Prevention), Farquhar CM, Jennifer Weuve, Lauren A. Wise, Missmer SA, Potgieter HC, Russ Hauser, Schwartz SM, Stacey A. Missmer, Strauss J, Taylor RN, U.S. Food and Drug Administration   +15 more
core   +3 more sources

The endocrine disruptor DEHP and the ECS: analysis of a possible crosstalk

Endocrine Connections, 2020
Studies of the last decade associated the environmental contamination by di-(2-ethylhexyl)-phthalate (DEHP) with obesity and endocrine malfunction. DEHP was found to interact with several receptors – among them are receptors of the endocannabinoid system
J. Ernst, Urszula Grabiec, K. Falk, F. Dehghani, Kristina Schaedlich   +4 more
semanticscholar   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Airborne environmental injuries and human health. [PDF]

, 2006
The concept that the environment in which we live can have detrimental effects on our health has existed for centuries. Obvious examples of substances that can cause human diseases include infectious agents, poisons, chemicals and other noxious agents ...
Borchers, Andrea T, Chang, Christopher, Gershwin, M Eric, Keen, Carl L   +3 more
core  

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Nonequilibrium stationary states and equilibrium models with long range interactions

, 2003
It was recently suggested by Blythe and Evans that a properly defined steady state normalisation factor can be seen as a partition function of a fictitious statistical ensemble in which the transition rates of the stochastic process play the role of ...
Arndt P F, Arndt P F, Binder K, Blythe R A, Blythe R A, Blythe R A, Blythe R A Evans M R, Brak R, Brak R, Brak R, Chaiken S, Chen W K, Dammer S M, De Gier J, Derrida B, Derrida B, Derrida B Enaud C Lebowitz J L, Gibbs J W, Jan de Gier, Kolomeisky A, Pearce P A, Richard Brak, Sasamoto T, Sasamoto T, Schütz G, Schütz G, Seneta E, Sylvester J J, Vladimir Rittenberg   +28 more
core   +1 more source

DEHP and DINP Induce Tissue- and Gender-Specific Disturbances in Fatty Acid and Lipidomic Profiles in Neonatal Mice: A Comparative Study.

Environmental Science and Technology, 2019
Di-isononyl phthalate (DINP) is considered one of the main industrial alternatives to di(2-ethylhexyl) phthalate (DEHP), a well-known chemical with various toxic effects including the disruption with lipid metabolism.
Yichao Huang, Fengjiang Sun, Hongli Tan, Yongfeng Deng, Zhiqiang Sun, Hexia Chen, Jing Li, Da Chen   +7 more
semanticscholar   +1 more source

Rosmarinic acid alleviates di-2-ethylhexyl phthalate (DEHP) -induced thyroid dysfunction via multiple inflammasomes activation.

Journal of Toxicological Sciences, 2020
DEHP (di-2-ethylhexyl phthalate), an environmental endocrine disruptor, is widely used in industrial products, particularly as plasticizers and softeners which could disrupt the function of the hypothalamic-pituitary-thyroid (HPT) axis.
Haoyu Wu, Kun Ma, Xiaolin Na
semanticscholar   +1 more source