Results 101 to 110 of about 60,390 (275)

The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]

open access: yes, 2015
The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA   +3 more
core   +3 more sources

Exercise training to preserve vitality capacity in ageing

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones   +12 more
wiley   +1 more source

Influence of the dissolution medium on the release of dehydroepiandrosterone from lipophilic suppositories

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2014
Suppositories with cocoa butter containing dehydroepiandrosterone (DHEA) without and with the addition of Span 80 and Tween 80 as surfactants with low and high HLB values were prepared.
Kasperek1 Regina   +4 more
doaj   +1 more source

X-RAY POWDER DIFFRACTION IN QUALITY CONTROL OF MEDICINES

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
X-ray powder diffraction is one of the methods used for detection and analysis of polymorphic forms of pharmaceutical substances. The article elucidates the concept of polymorphism, briefly explains physical characteristics of this phenomenon, conditions
V. S. Kuzmin   +2 more
doaj   +1 more source

Testosterone modulates multispectral oscillatory activity serving performance of motor sequences in typically developing youth

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Increases in testosterone are associated with developmental changes in motor‐related neural oscillations in youth. Abstract Motor control is critical to daily functioning and undergoes significant refinement throughout youth. Although the effects of age on the underlying brain circuitry have been well characterized, fewer studies
Jackson Derby   +12 more
wiley   +1 more source

The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]

open access: yes, 1995
In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G   +3 more
core   +1 more source

Hypoxia and dehydroepiandrosterone in old age: a mouse survival study

open access: yesRespiratory Research, 2006
Background Survival remains an issue in pulmonary hypertension, a chronic disorder that often affects aged human adults. In young adult mice and rats, chronic 50% hypoxia (11% FIO2 or 0.5 atm) induces pulmonary hypertension without threatening life.
Quillard Janine   +2 more
doaj   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

open access: yesBiological Reviews, Volume 101, Issue 2, Page 970-1002, April 2026.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis   +3 more
wiley   +1 more source

Effects of DHEA and DHEAS in Neonatal Hypoxic–Ischemic Brain Injury

open access: yesAntioxidants
Neonatal brain injury remains a significant issue with limited treatment options. This study investigates the potential of the endogenous neurosteroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) as neuroprotective agents, building on ...
Elena Mayer   +6 more
doaj   +1 more source

Restoration of Gut Microbiota and Metabolic Homeostasis by Lacticaseibacillus paracasei Zhang in Azithromycin‐Induced Dysbiosis

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study investigated whether Lacticaseibacillus paracasei Zhang could alleviate the gut microbiota imbalance and its systemic consequences caused by antibiotics. Mice treated with azithromycin exhibited gut microbiota disorders, and subsequent probiotic intervention was carried out.
Xiaoye Liu   +4 more
wiley   +1 more source

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