Results 111 to 120 of about 39,361 (246)

Correlation Analysis of Hypothalamic-Pituitary-Adrenal Axis Hormone Levels in Hair before Stroke Onset and Mood Disorders after Stroke

康复学报
ObjectiveTo explore the expression of hypothalamic-pituitary-adrenal (HPA) axis related hormones such as cortisol (F), cortisone (E) and dehydroepiandrosterone (DHEA) in hair before the onset of stroke and their correlation with post-stroke mood ...
WANG Tiantian, JIA Yuanyuan, QI Deyi, DENG Huihua, MENG Dianhuai   +4 more
doaj  

Effects of DHEA and DHEAS in Neonatal Hypoxic–Ischemic Brain Injury

Antioxidants
Neonatal brain injury remains a significant issue with limited treatment options. This study investigates the potential of the endogenous neurosteroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) as neuroprotective agents, building on ...
Elena Mayer, Ira Winkler, Eva Huber, Martina Urbanek, Ursula Kiechl-Kohlendorfer, Elke Griesmaier, Anna Posod   +6 more
doaj   +1 more source

Neurosteroid Transport in the Brain: Role of ABC and SLC Transporters

Frontiers in Pharmacology, 2018
Neurosteroids, comprising pregnane, androstane, and sulfated steroids can alter neuronal excitability through interaction with ligand-gated ion channels and other receptors and have therefore a therapeutic potential in several brain disorders.
Markus Grube, Paul Hagen, Gabriele Jedlitschky   +2 more
doaj   +1 more source

Identification of Synthetic Urine by Analysis of Stable Carbon and Nitrogen Isotope Ratios and Comparison to Established GC‐MS/MS and LC‐MS/MS Analysis

Drug Testing and Analysis, Volume 18, Issue 8, Page 1145-1151, August 2026.
This study compared GC‐MS/MS, EA‐IRMS, and LC‐MS/MS for detecting synthetic and manipulated urine samples in doping control and forensic analysis. EA‐IRMS proved particularly effective for identifying mixtures of synthetic and authentic urine, providing a reliable complement to established authenticity testing methods.
Frank Hülsemann, Laura Franke, Dirk K. Wissenbach, Gregor Fußhöller, Mario Thevis   +4 more
wiley   +1 more source

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, Volume 82, Issue 8, Page 7903-7914, August 2026.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source

Anorectic effect of dehydroepiandrosterone combined with dexfenfluramine or thionisoxetine [PDF]

, 2001
Free feeding rats given supplementary 1 h access per day to a palatable dessert test meal were tested for the anorectic effect of dehydroepiandrosterone alone or in combination with either the serotonin releasing agent dexfenfluramine or the ...
Robertson, K, Rowland, N E, Marshall, Misty   +2 more
core  

Influence of the dissolution medium on the release of dehydroepiandrosterone from lipophilic suppositories

Current Issues in Pharmacy and Medical Sciences, 2014
Suppositories with cocoa butter containing dehydroepiandrosterone (DHEA) without and with the addition of Span 80 and Tween 80 as surfactants with low and high HLB values were prepared.
Kasperek1 Regina, Galczynski Krzysztof, Nalesniak Magdalena, Iwaniak Karol, Poleszak Ewa   +4 more
doaj   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 4, Page 424-431, August 2026.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

Insulin Resistance Emerges Early After Glucocorticoid Treatment in Adult Patients With 21‐Hydroxylase Deficiency

Journal of Diabetes, Volume 18, Issue 8, August 2026.
In adults with 21‐hydroxylase deficiency, ongoing glucocorticoid therapy, especially dexamethasone, was the main risk factor for insulin resistance. New‐onset insulin resistance emerged early, highlighting the need for metabolic monitoring within the first 1–2 years of treatment. ABSTRACT Background Metabolic disorders, particularly insulin resistance (
Chenchen Dong, Wencui Wang, Sichang Zheng, Lingxin Deng, Rulai Han, Weiqing Wang, Guang Ning, Shouyue Sun, Lei Ye   +8 more
wiley   +1 more source

Prolactin in high‐metabolic risk pregnancies: Associations with maternal obesity and metabolic health

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1490-1501, August 2026.
Higher maternal BMI before and during early pregnancy is associated with lower prolactin levels across gestation and a reduced prolactin rise. Prolactin in pregnancy may reflect maternal metabolic health and has potential relevance to lactation outcomes.
Kate Rassie, Simon Alesi, Adriana C. H. Neven, Taitum Mason, Eveline Jona, Stacey J. Ellery, Joanne Enticott, Aya Mousa, Anju E. Joham, David Simmons, Helena Teede, on behalf of the TOBOGM Core Investigator Group   +11 more
wiley   +1 more source