Results 111 to 120 of about 60,390 (275)

The metabolism of dehydroepiandrosterone sulfate and dehydroepiandrosterone

The Aging Male, 1998
Dehydroepiandrosterone sulfate (DHEAS), one of the major secretory products of the adrenal glands, is cleared very slowly from the circulation with a t1/2 of 13.7 h and a metabolic clearance rate of 15.5 1/day. This slow metabolism is due, largely, to its strong binding to serum albumin, and its renal tubular reabsorption.
openaire   +1 more source

Is Smart Working Beneficial for Workers’ Wellbeing? A Longitudinal Investigation of Smart Working, Workload, and Hair Cortisol/Dehydroepiandrosterone Sulfate during the COVID-19 Pandemic

, 2023
Alessandra Falco, Damiano Girardi, Achim Elfering, Tanja Peric, Isabella Pividori, Laura Dal Corso   +5 more
openalex   +1 more source

Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Sarcopenia is an age‐related condition characterized by progressive muscle mass, strength and physical performance declines, contributing to frailty and adverse health outcomes. Despite increasing interest in molecular biomarkers, longitudinal data with external validation are limited.
Sung Hye Kong, Ok Hee Jeon, Ji Yeon Kim, Miji Kim, Jinhee Kim, Seung Shin Park, Hak Chul Chang, Chang Won Won, Dohyun Han   +8 more
wiley   +1 more source

Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry [PDF]

, 2013
Consequences of alternative H-bonding: Raman spectra of oxygenated intermediates of Nanodisc-incorporated human CYP17 in the presence of natural substrates (pregnenolone and progesterone) directly confirm that substrate structure effectively alters ...
Gregory, Michael, Kincaid, James R., Mak, Piotr J., Sligar, Stephen G.   +3 more
core   +2 more sources

Correlation Analysis of Hypothalamic-Pituitary-Adrenal Axis Hormone Levels in Hair before Stroke Onset and Mood Disorders after Stroke

康复学报
ObjectiveTo explore the expression of hypothalamic-pituitary-adrenal (HPA) axis related hormones such as cortisol (F), cortisone (E) and dehydroepiandrosterone (DHEA) in hair before the onset of stroke and their correlation with post-stroke mood ...
WANG Tiantian, JIA Yuanyuan, QI Deyi, DENG Huihua, MENG Dianhuai   +4 more
doaj  

Dehydroepiandrosterone increases β‐cell mass and improves the glucose‐induced insulin secretion by pancreatic islets from aged rats [PDF]

, 2005
Mayrin Correa Medina, L C. Souza, Luciana C. Caperuto, Gabriel Forato Anhê, Angélica M. Amanso, Vicente P. A. Teixeira, Silvana Bordin, Ângelo Rafael Carpinelli, Luiz Roberto Britto, Renato L. Barbieri, Maria Inês Borella, Carla Roberta de Oliveira Carvalho   +11 more
openalex   +1 more source

Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' subfamily, recent cryo‐EM structures of the androgens 5α‐dihydrotestosterone (5α‐DHT) and methenolone bound to ADGRD1 revealed a putative steroid ...
Bethany Fleming, Abdul‐Akim Guseinov, Irina G. Tikhonova, Graeme Milligan, Nicole A. Perry‐Hauser   +4 more
wiley   +1 more source

Resonance Raman Spectroscopy Reveals that Substrate Structure Selectively Impacts the Heme-Bound Diatomic Ligands of CYP17 [PDF]

, 2013
An important function of steroidogenic cytochromes P450 is the transformation of cholesterol to produce androgens, estrogens, and the corticosteroids.
Gregory, Michael C., Kincaid, James R., Mak, Piotr J., Sligar, Stephen G.   +3 more
core   +2 more sources

Physiological Responses to Virtual Reality‐Based Stress Regulation and Relaxation Interventions: A Systematic Review

Stress and Health, Volume 42, Issue 2, April 2026.
ABSTRACT Physiological markers are increasingly used to monitor individuals undergoing Virtual Reality (VR) stress interventions. However, several challenges arise when employing these markers to assess the impact of VR stress interventions. This systematic review synthesises and critically discusses the literature on VR stress interventions across ...
Lisanne M. Robbemond, Matthijs L. Noordzij, Catheleine M. G. van Driel, Wim Veling   +3 more
wiley   +1 more source

Isaria fumosorosea KCh J2 Entomopathogenic Strain as an Effective Biocatalyst for Steroid Compound Transformations

Molecules, 2017
The catalytic activity of enzymes produced by an entomopathogenic filamentous fungus (Isaria fumosorosea KCh J2) towards selected steroid compounds (androstenedione, adrenosterone, progesterone, 17α-methyltestosterone and dehydroepiandrosterone) was ...
Ewa Kozłowska, Monika Dymarska, Edyta Kostrzewa-Susłow, Tomasz Janeczko   +3 more
doaj   +1 more source