Results 61 to 70 of about 12,662 (158)
Sex‐Specific Factors Influencing HIV Infection
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley +1 more source
Adrenarche as a regulator of sensitivity to early adversity
Abstract The human brain is highly sensitive to early adversity, which can have long‐term consequences for later mental health. It is also a time of rapid learning of social, motor and other skills, including language. It is proposed that pre‐adrenarche, the only epoch in human development in which cortisol is not accompanied by dehydroepiandrosterone (
J. Herbert
wiley +1 more source
Cholesterol sulfate in human physiology: what's it all about?
Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate.
Charles A. Strott, Yuko Higashi
doaj +1 more source
Metabolism of Dehydroepiandrosterone Sulfate and Estrone-Sulfate by Human Platelets
The aim of the present research was to study the uptake of DHEAS, and to establish the intracrine capacity of human platelets to produce sex steroid hormones. The DHEAS transport was evaluated through the uptake of [3H]-DHEAS in the presence or absence of different substrates through the organic anion transporting polypeptide (OATP) family.
Garrido, A. +3 more
openaire +4 more sources
An allostatic load domain‐specific metabolic profile in young adults: The African‐PREDICT study
Abstract figure legend An allostatic load domain‐specific metabolic profile in young adults: The African‐PREDICT study Abstract Allostatic load scores (ALSs) quantify the cumulative physiological burden of sustained stress across neuro‐endocrine, metabolic, cardiovascular and inflammatory domains; however ALS is heterogeneous in nature.
Nevah Joubert +4 more
wiley +1 more source
Introduction: Decreased anabolic to catabolic ratio during menopause, can lead to a reduction in muscle size and strength. Hence, the current study amed to investigate the effect of eight weeks of resistance exercise on adaptive responses of cortisol and
R Zare, SR Attarzade Hosseini, M Fathi
doaj
Abstract Warfighters face significant risk of mild traumatic brain injury (mTBI) during operations and training. We performed a double‐blind, randomized, placebo‐controlled trial to: (1) determine head strike (HS) incidence, during US Army Basic Airborne Course's Improved Swing Landing Trainer (ISLT) training, (2) test protective efficacy of ketone ...
Toshiya Miyatsu +19 more
wiley +1 more source
Background: It is supposed that hypoandrogenism may be involved in the pathogenesis of rheumatoid arthritis (RA). Testosterone and dehydroepiandrosterone sulfate (DHEAs) levels decrease in body fluids of patients with RA.
Mahin Lashkari +3 more
doaj +1 more source
Serum levels of DHEA sulfate are inversely associated with cardiovascular death in men, and urinary dehydroepiandrosterone (DHEA) levels are inversely associated with clinical manifestations of coronary artery disease. These observations may be related to the antiproliferative effects of DHEA, resulting in inhibition of atherosclerotic intimal ...
Herrington, David M. +6 more
openaire +2 more sources
Testosterone increases circulating dehydroepiandrosterone sulfate levels in the male rhesus macaque
The adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are two of the most abundant hormones in the human circulation. Furthermore, they are released in a circadian pattern and show a marked age-associated decline. Adult levels of DHEA
Krystina eSorwell +2 more
doaj +1 more source

