Results 91 to 100 of about 1,320,603 (414)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Identification of putative methanol dehydrogenase (moxF) structural genes in methylotrophs and cloning of moxF genes from Methylococcus capsulatus bath and Methylomonas albus BG8 [PDF]

open access: yes, 1988
An open-reading-frame fragment of a Methylobacterium sp. strain AM1 gene (moxF) encoding a portion of the methanol dehydrogenase structural protein has been used as a hybridization probe to detect similar sequences in a variety of methylotrophic bacteria.
Haygood, Margo G.   +2 more
core  

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria.

open access: yesBiochemical Journal, 1980
Submitochondrial particles from bovine heart in which NADH dehydrogenase is reduced by either addition of NADH and rotenone or by reversed electron transfer generate 0.9 +/- 0.1 nmol of O2-/min per mg of protein at pH 7.4 and at 30 degrees C.
J. Turrens, A. Boveris
semanticscholar   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

PARÁMETROS BIOQUÍMICOS ENZIMÁTICOS (ALT, AST, ALP, Γ-GT, LDH) EN NIÑOS CON LEUCEMIA LINFOBLÁSTICA AGUDA ANTES DEL TRATAMIENTO ANTINEOPLÁSICO

open access: yesHorizonte Médico, 2015
Objective: To determine the enzymatic biochemical parameters (glutamic pyruvic transaminase (ALT), glutamic oxaloacetic transaminase (AST), alkaline phosphatase (ALP), gamma glutamyltransferase (γ-GT), and lactate dehydrogenase (LDH)) in children with ...
Jeél Moya S, Liz Pio D
doaj  

Synergistic Effects of Exogenous Nutrient Ions on the Real-Time Cadmium Extraction by an Accumulator

open access: yesAgriculture
Bidens tripartita L. is a cadmium (Cd) accumulator. However, the real-time influx or efflux of Cd2+ around its root apex has not yet been performed. The object of this experiment was to compare the roles of added ions in solution on dynamic Cd extraction
Siqi Wang   +8 more
doaj   +1 more source

In vitro effects of petroleum refinery wastewater on dehydrogenase activity in marine bacterial strains

open access: yesRevista Ambiente & Água, 2010
Toxicity of oil refinery effluent on four bacteria strains isolated from refinery effluent impacted river water sample was assessed via dehydrogenase assay.
Gideon O. Abu   +1 more
doaj   +1 more source

Selective enrichment of heterotrophic nitrifiers Alcaligenaceae and Alcanivorax spp. from industrial wastewaters

open access: yesAIMS Microbiology, 2020
Removal of nitrogen from wastewaters (WW) represents a global problem. The low nitrification rate during WW treatment is often caused by ecotoxicity. This problem is attributed mostly to the industrial WW.
Mārtiņš Kalniņš   +6 more
doaj   +1 more source

The effects of feeding with organic waste by terrestrial isopod Philoscia Muscorum on enzyme activities in an incubated soil

open access: yesEurasian Journal of Soil Science, 2023
Soil fauna are important biological factors that affect litter decomposition and play an important role in the release of nutrients and improve soil enzyme activities. This study focused on the effects of isopods on enzymatic activities of soil.
Sholpan S. Muminova   +5 more
doaj   +1 more source

Glutamate biosynthesis in Bacillus azotofixans. 15N NMR and enzymatic studies [PDF]

open access: yes, 1988
Pathways of ammonia assimilation into glutamic acid in Bacillus azotofixans, a recently characterized nitrogen-fixing species of Bacillus, were investigated through observation by NMR spectroscopy of in vivo incorporation of 15N into glutamine and ...
Kanamori, Keiko   +2 more
core  

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