Results 111 to 120 of about 1,422,916 (387)

Latent acetylcholinesterase in secretory vesicles isolated from adrenal medulla [PDF]

, 1981
A new procedure is described for the preparation of highly purified and stable secretory vesicles from adrenal medulla. Two forms of acetylcholinesterase, a membrane bound form as well as a soluble form, were found within these vesicles.
Abbs, Anton, Bergmeyer, Blakeborough, Carty, Casey, Chubb, Chubb, Creutz, Dahl, Ekerdt, Ellman, Famborough, Farquar, Gratzl, Gratzl, Gratzl, Ingebretsen, Johnson, Laemmli, Lagercrantz, Leighton, Little, Lowry, Lowry, Meyer, Morris, Morris, Omaye, Palade, Rotundo, Rotundo, Schmidt, Smilowitz, Somogyi, Terland, Terland, Trifaro, Winkler   +38 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Lactic Dehydrogenase Virus

Virology monographs. Die Virusforschung in Einzeldarstellungen, 2022
Virology Monographs, Die Virusforschung, IN Einzeldarstellungen, K. Rowson   +3 more
semanticscholar   +1 more source

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

Journal of Clinical Oncology, 2009
PURPOSE Unexpected mutations affecting the isocitrate dehydrogenase (IDH1) gene at codon 132 have been found in 12% of glioblastomas. PATIENTS AND METHODS IDH1 codon 132 sequencing was performed in a series of 404 patients with glioma (100 grade 2, 121
M. Sanson, Y. Marie, S. Paris, A. Idbaih, J. Laffaire, F. Ducray, S. El Hallani, B. Boisselier, K. Mokhtari, K. Hoang-Xuan, J. Delattre   +10 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase

BMC Research Notes, 2009
BackgroundThe shikimate pathway is an attractive target for the development of antitubercular agents because it is essential in Mycobacterium tuberculosis, the causative agent of tuberculosis, but absent in humans. M.
Valnês S. Rodrigues, A. Breda, D. Santos, L. A. Basso   +3 more
semanticscholar   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Atividade microbiana do solo em pomar de laranja em resposta ao cultivo de adubos verdes Soil microbialactivities in orchard citrus as a response to green manure cultivation

Revista Brasileira de Fruticultura, 2009
Adubos verdes (AVs) são condicionadores do solo utilizados para a melhoria da estrutura e fertilidade do solo. Este estudo avaliou o efeito de Crotalaria spectabilis Roth (crotalária), Cajanus cajan (L) Millsp (guandu) e Brachiaria decumbens Stapf ...
Thais Nucci Buzinaro, José Carlos Barbosa, Ely Nahas   +2 more
doaj   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Simulation of a surface spill of different diesel/biodiesel mixtures in an ultisol, using natural attenuation and bioaugmentation/biostimulation

Anais da Academia Brasileira de Ciências
Accidents caused by leaks and/or spills on soils need to be addressed. Natural attenuation, biostimulation and bioaugmentation can be useful bioremediation strategies for decontamination processes in soils of diesel/biodiesel mixtures.
DANIEL D. MEYER, SABRINA A. BEKER, KARINA HECK, MARIA DO CARMO R. PERALBA, FÁTIMA M. BENTO   +4 more
doaj   +1 more source