Results 111 to 120 of about 1,025,936 (342)

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Organic Composition of Bone : Localization of Isocitric Dehydrogenase in Femurs [PDF]

, 1958
R. van Reen, F.L. Losee
openalex   +1 more source

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.

Cell Metabolism, 2006
Jung-whan Kim, Irina Tchernyshyov, G. Semenza, C. Dang   +3 more
semanticscholar   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

STUDIES ON SUCCINIC DEHYDROGENASE

, 1956
Edna B. Kearney, Thomas P. Singer
openalex   +2 more sources

Preparation of a Highly Active Alcohol Apo-dehydrogenase from Yeast [PDF]

, 1937
M Sreenivasaya
openalex   +1 more source

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Cell, 2016
E. Mills, B. Kelly, A. Logan, Ana S. H. Costa, M. Varma, C. Bryant, Panagiotis Tourlomousis, J. Däbritz, E. Gottlieb, I. Latorre, S. Corr, G. McManus, D. Ryan, H. Jacobs, H. Jacobs, M. Szibor, M. Szibor, M. Szibor, R. Xavier, T. Braun, C. Frezza, M. Murphy, L. O’Neill   +22 more
semanticscholar   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

Clinical pharmacology and therapy, 2018
U. Amstutz, L. Henricks, S. Offer, Julia M. Barbarino, J. Schellens, J. Swen, T. Klein, H. McLeod, K. Caudle, R. Diasio, M. Schwab   +10 more
semanticscholar   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source