Results 201 to 210 of about 1,224,293 (342)

Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase

, 2016
Juliya Kalinina, Jun Young Ahn, Narra S. Devi, Liya Wang, Yuancheng Li, Jeffrey J. Olson, Michael Glantz, Thomas W. Smith, Ella L. Kim, Alf Giese, Randy L. Jensen, Clark C. Chen, Bob S. Carter, Hui Mao, Miao He, Erwin G. Van Meir   +15 more
openalex   +2 more sources

Polyol dehydrogenases. 3. Galactitol dehydrogenase and d-iditol dehydrogenase [PDF]

Biochemical Journal, 1956
openaire   +2 more sources

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Taxonomic distribution of alkane synthesizing aldehyde dehydrogenases across bacteria, fungi, plants, and animals. [PDF]

Biotechnol Biofuels Bioprod
Ito M, Sui YA, Okada N, Kitamura N, Kishino S, Muramatsu M, Ogawa J.   +6 more
europepmc   +1 more source

Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase by 6-Azaandrost-4-en-3-ones: Optimization of the C17 Substituent

, 1995
Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Roger N. Hiner, George F. Dorsey, Robert A. Noe, Rayomand J. Unwalla, Kenneth W. Batchelor, H. Neal Bramson, J. Darren Stuart, Stephanie L. Schweiker, J. VAN ARNOLD, D. Mark Bickett, Marcia L. Moss, Gaochao Tian, Frank W. Lee, Timothy K. Tippin, Michael K. James, Mary K. Grizzle, James E. Long, Dallas K. Croom   +20 more
openalex   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid-Induced Neurotoxic Phenotype of Astrocytes. [PDF]

Glia
Esteve D, Bresque M, Okhuevbie D, Ramachandran S, Pehar M, Vargas MR.   +5 more
europepmc   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Three-generations low-altitude adaptations: Embryonic development, eggshell properties, and metabolic gene expression of snowy white chickens originated from Tibetan-plateau. [PDF]

Poult Sci
Peng L, Wu L, Hu Y, Zhang Y, Wang Y, Ye L, Zhao X.   +6 more
europepmc   +1 more source

Phenotypic variability in 17β‐hydroxysteroid dehydrogenase‐3 deficiency and diagnostic pitfalls

, 2007
Yung Seng Lee, Jeremy Kirk, R Stanhope, D I Johnston, Sharon Harland, Richard J. Auchus, Stefan Andersson, Ieuan A. Hughes   +7 more
openalex   +2 more sources