Results 201 to 210 of about 1,320,603 (414)

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.

open access: yesCell Metabolism, 2016
Vicky Lampropoulou   +17 more
semanticscholar   +1 more source

Biomimetic Co‐delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a novel HCC treatment using poly lactic‐co‐glycolic acid (PLGA) nanoparticles encased in HCC cell membranes to co‐deliver Lenvatinib and FePt nanoparticles. This approach improves treatment efficacy by enhancing ferroptosis and apoptosis.
Feichao Xuan   +11 more
wiley   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Structural and Functional Properties of the H and M Subunits of Lactic Dehydrogenases [PDF]

open access: yes
Structural and functional properties of H and M protein subunits of lactic ...
Fondy, T. P., Kaplan, N. O.
core   +1 more source

Characterisation of a chlororespiratory pathway in Beta vulgaris and Trifolium repens : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, New Zealand [PDF]

open access: yes, 2002
The chloroplast respiratory pathway (chlororespiration) is postulated to interact with the photosynthetic pathway through the plastoquinone (PQ) pool. Two enzymes are proposed to operate in the pathway: an NAD(P)H dehydrogenase that is homologous to the ...
Winger, Alison Marie
core  

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

open access: yesAdvanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang   +14 more
wiley   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu   +8 more
wiley   +1 more source

Non‐Surgical, In‐Stent Membrane Bioelectronics for Long‐Term Intracranial Pressure Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
This image shows a sequence of long‐term intracranial pressure monitoring using non‐surgical, in‐stent membrane bioelectronics. Abstract Traditional intracranial pressure (ICP) monitoring methods, using intraventricular catheters, face significant limitations, including high invasiveness, discrete data, calibration complexities, and drift issues, which
Jimin Lee   +9 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

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