Results 71 to 80 of about 29,531 (259)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

$C^1$-smooth dependence on initial conditions and delay: spaces of initial histories of Sobolev type, and differentiability of translation in $L^p$

Electronic Journal of Qualitative Theory of Differential Equations, 2019
The objective of this paper is to clarify the relationship between the $C^1$-smooth dependence of solutions to delay differential equations (DDEs) on initial histories (i.e., initial conditions) and delay parameters. For this purpose, we consider a class
Junya Nishiguchi
doaj   +1 more source

Numerical methods and hypoexponential approximations for gamma distributed delay differential equations. [PDF]

IMA J Appl Math, 2022
Cassidy T, Gillich P, Humphries AR, van Dorp CH.   +3 more
europepmc   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

L^p perturbations in delay differential equations

Electronic Journal of Differential Equations, 2001
We present extensions and new proofs for the asymptotic formulae and theorems in Cooke [3] for differential equations with variable delay. Explicit asymptotic formulae, examples and comparisons with the classical results are given here.
Samuel Castillo, Manuel Pinto
doaj  

An Efficient Numerical Scheme for Solving a Fractional-Order System of Delay Differential Equations. [PDF]

Int J Appl Comput Math, 2022
Kumar M.
europepmc   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Modified wavelets–based algorithm for nonlinear delay differential equations of fractional order

Advances in Mechanical Engineering, 2017
Most of the physical phenomena located around us are nonlinear in nature and their solutions are of great significance for scientists and engineers. In order to have a better representation of these physical phenomena, fractional calculus is developed ...
Muhammad Asad Iqbal, Muhammad Shakeel, Syed Tauseef Mohyud-Din, Muhammad Rafiq   +3 more
doaj   +1 more source

Stability in distribution for uncertain delay differential equations based on new Lipschitz condition. [PDF]

J Ambient Intell Humaniz Comput, 2022
Gao Y, Jia L.
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source