Results 81 to 90 of about 29,531 (259)

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

Oscillation of Fourth-Order Functional Differential Equations with Distributed Delay

open access: yesAxioms, 2019
In this paper, the authors obtain some new sufficient conditions for the oscillation of all solutions of the fourth order delay differential equations.
Clemente Cesarano, Omar Bazighifan
doaj   +1 more source

Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations. [PDF]

open access: yesBr J Clin Pharmacol, 2022
Liu F   +6 more
europepmc   +1 more source

Noncontinuable Solutions of Differential-Delay Equations [PDF]

open access: yesProceedings of the American Mathematical Society, 1969
(4) F I is bounded on [to, T] X C" for each to, T and each A > 0. Condition (4) usually holds for equations that appear in the literature. It is stated here to emphasize that the theory of continuability of solutions can be fairly natural when (4) is assumed: Let x be a noncontinuable solution on [to, T) of (1), where to-q Rd is continuous.
openaire   +1 more source

Geometry of Stochastic Delay Differential Equations

open access: yesElectronic Communications in Probability, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Catuogno, Pedro, Ruffino, Paulo
openaire   +3 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Peculiar spline collocation method for solving rough and stiff delay differential problems

open access: yesJournal of Numerical Analysis and Approximation Theory, 2004
As well known, solutions of delay differential equations (DDEs) are characterized by low regularity. In particular solutions of neutral delay differential equations (NDDEs) frequently exhibit discontinuities in the first derivative so that the ...
F. Calio, E. Marchetti, R. Pavani
doaj   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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