Results 91 to 100 of about 38,967 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Homoclinic snaking in a neutral delay model of a transmission line oscillator [PDF]

open access: yes, 2006
In a transmission line oscillator (TLO) a linear wave travels along a piece of cable, the transmission line, and interacts with terminating electrical components.
Wilson, RE, Barton, DAW, Krauskopf, B
core  

Oscillation of Bounded Solutions of Delay Differential Equations [PDF]

open access: yes
The purpose of this paper is to give new oscillation criteria for second-order delay differential equations y″(t)=p(t)y(τ(t)).
Jozef Dzurina
core   +1 more source

On the oscillation of delay differential equations with real coefficients

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1999
A set of necessary conditions and another set of sufficient conditions for the oscillation of all the solutions of x˙(t)+∑i=1npix(t−τi)=0,         where   pi∈ℝ,  τi∈ℝ+,    i=1,2,…,n                                   (*) are proved.
H. A. Agwo
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Numerical solutions of neutral stochastic functional differential equations [PDF]

open access: yes, 2008
This paper examines the numerical solutions of neutral stochastic functional differential equations (NSFDEs) $d[x(t)-u(x_t)]=f(x_t)dt+g(x_t)dw(t)$, $t\geq 0$.
Wu, Fuke   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Periodic solution for a delay integro-differential equation in biomathematics [PDF]

open access: yes, 2003
Sufficient conditions for the existence and uniqueness of periodic solution of a delay integro-differential equation which arise in biomathematics are given.
Bica, Alexandru Mihai, Muresan, Sorin
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Class of Fractional Degenerate Evolution Equations with Delay [PDF]

open access: yes, 2020
We establish a class of degenerate fractional differential equations involving delay arguments in Banach spaces. The system endowed by a given background and the generalized Showalter–Sidorov conditions which are natural for degenerate type ...
Amar Debbouche, Vladimir E. Fedorov
core   +1 more source

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