Results 241 to 250 of about 2,087,247 (387)

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

Delayed hypersensitivity reaction to orodispersible budesonide in a case with eosinophilic esophagitis. [PDF]

BMC Gastroenterol, 2020
Andrist CM, Jörg L, Greuter T, Gschwend A, Straumann A, Helbling A.   +5 more
europepmc   +1 more source

Contact sensitivity in the murine oral mucosa. I. An experimental model of delayed-type hypersensitivity reactions at mucosal surfaces

, 1991
E. E. Ahlfors, Cécil Czerkinsky
openalex   +2 more sources

Specific Restoration of Delayed Hypersensitivity by Lymphoid Tissue Extracts [PDF]

, 1977
Jon A. Green, Juliann Williams, Hilton B. Levy   +2 more
openalex   +1 more source

Modeling cerebral palsy in animals

Developmental Medicine &Child Neurology, EarlyView.
Abstract Advancements in the treatment of cerebral palsy depend on animal research. Yet, most animal models have not been fully evaluated for spasticity and dystonia using clinically relevant measures of altered tone or movement patterns, which form the basis for diagnosing people with the condition.
Katharina A. Quinlan, Emily J. Reedich, Elvia Mena Avila, Brendan C. Moline, Landon T. Genry, Megan R. Detloff, Benjamin R. Katholi, Deborah Gaebler‐Spira, Bhooma R. Aravamuthan   +8 more
wiley   +1 more source

Delayed‐Type Hypersensitivity to Hen Egg‐White Lysozyme: I. The Surface Phenotypes of Suppressor T Cells Induced by Intravenous Injection of Lysozyme‐Modified Spleen Cells, and Their Moleculor Interactions [PDF]

, 1982
Kenji Okuda, Norihisa Ishii, Z Ikezawa, Toyozoh Takahashi, Katsuji Arai, I Tadokoro   +5 more
openalex   +1 more source

MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity

Journal of Immunology, 2011
Thomas X. Lu, Jochen C. Hartner, E. Lim, V. Fabry, M. Mingler, Eric T. Cole, S. Orkin, B. Aronow, M. Rothenberg   +8 more
semanticscholar   +1 more source

Low immunogenicity of insulin efsitora alfa in participants with type 1 and type 2 diabetes mellitus

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate treatment‐emergent antidrug antibodies (TE ADA) in once‐weekly basal insulin efsitora‐treated participants with type 1 and type 2 diabetes mellitus (T1DM and T2DM) from 5 phase 3 clinical trials and their potential impact on pharmacokinetics, efficacy and safety.
Yun Wang, Sihe Wang, Wei Wang, Xiaoqi Li, Jennifer Leohr, Vitoria Pires, Michelle L. Katz, Christopher J. Child, Robert J. Konrad   +8 more
wiley   +1 more source

The Immunopathobiology of Syphilis: The Manifestations and Course of Syphilis Are Determined by the Level of Delayed-Type Hypersensitivity

American journal of dermatopathology, 2011
J. Carlson, Ganary Dabiri, B. Cribier, S. Sell   +3 more
semanticscholar   +1 more source

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss, Vi‐Huong Nguyen‐Michel, Espártaco Moraes Ribeiro, Virginie Lambrecq, Aurélie Hanin, Sophie Demeret, Vincent Navarro   +6 more
wiley   +1 more source