TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha +9 more
wiley +1 more source
Safety of cephalosporins in penicillin class severe delayed hypersensitivity reactions. [PDF]
Trubiano JA +6 more
europepmc +1 more source
Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni +19 more
wiley +1 more source
Immunodeficiency Diseases and Tumor Immunobiology [PDF]
Abramoff, Peter A., Duquesnoy, Rene J.
core +1 more source
Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGu)-poly(DLAla)--poly(LLys). I. Expression of the genetic defect at two phases of the immune process. [PDF]
Gideon Strassmann +2 more
openalex +1 more source
Delayed Hypersensitivity: Indicator of Acquired Failure of Host Defenses in Sepsis and Trauma
J. Meakins +6 more
semanticscholar +1 more source
Chronic spontaneous urticaria affects more females than males, with predominance starting at age 31. The rates of several symptoms, including angioedema, sleep disturbance and systemic symptoms, are significantly higher in females than in males. Overall, females face greater burden and poorer urticaria control.
Emek Kocatürk +40 more
wiley +1 more source
Omeprazole Induced Rapid Drug Reaction with Eosinophilia, Systemic Symptoms, and Cross-Reactivity in Delayed-Type Hypersensitivity Associated with Proton-Pump Inhibitors: A Case Report and Literature Review [PDF]
Kanokkarn Pinyopornpanish +6 more
openalex +1 more source
Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta +5 more
wiley +1 more source
A rare case of delayed hypersensitivity reaction to metal ions secondary to a remnant pedicle screw fragment after spinal arthrodesis. [PDF]
Kim J.
europepmc +1 more source

