Results 101 to 110 of about 338,573 (328)
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
INFLUENCIA DE LA CONCEPCIÓN DELIBERATIVA DE LA DEMOCRACIA EN EL PROCEDIMIENTO LEGISLATIVO COLOMBIANO [PDF]
Ratio Juris, 2014 Given that the decision making in legislative matter and of constitu- tional reform in Colombia is exercised by a representative body, the Congress - , and also citizen participation mechanisms that serve to promote or control the work of that organ are ...
Andrés Díaz del Castillo
doaj
Democratic Self-Determination and the Intentional Building of Consensus
Journal of Deliberative Democracy, 2019 This paper defends two fundamental but under-theorized insights coming from the theory of deliberative democracy. The first is that consensus is valuable as a precondition of democratic collective self-determination, since it ensures that democratic ...
Valeria Ottonelli
doaj +2 more sources
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
The State of Our Field: Introduction to the Special Issue
Journal of Deliberative Democracy, 2014 This article introduces the special “State of the Field” issue. The essay highlights some of the key tensions that our field is wrestling with at the moment, and advocates that we think carefully about the terms we use to describe our work.
Laura Black +2 more
doaj +2 more sources
Recent Work on Internal and External Reasons [PDF]
, 2017 This paper examines some recent arguments for internalism that (i) appeal to an analogy between practical and theoretical reasons, (ii) look toward our practices of reasoning with others, or (iii) tie reasons to good deliberation.
Brunero, John
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
What did we learn about citizen involvement in the health policy process: lessons from Brazil
Journal of Deliberative Democracy, 2013 In this paper I argue that citizen involvement helped to promote a more equitable distribution of public health services in Brazil. This achievement involved a balance of contributions from social actors and health system managers in forging policy ...
Vera Schattan Coelho
doaj +2 more sources