Results 121 to 130 of about 63,663 (310)

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

The Civic Benefits of Imperfect Deliberation

open access: yes, 2008
Normative theories of deliberative democracy stake claims that deliberation, if done correctly, can enhance citizens’ trust in authorities, foster a greater understanding of political issues and the element of compromise in politics, and increase the ...
Grimes, Marcia F
core  

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Focus Group Discussions as Sites for Public Deliberation and Sensemaking Following Shared Political Documentary Viewing

open access: yes, 2017
This study examines the potential that shared political documentary viewing coupled with public deliberation via focus group discussion has for political sensemaking and civic engagement.
Kenski, Kate   +3 more
core  

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Finding a Seat for Social Justice at the Table of Dialogue and Deliberation

open access: yes, 2014
What does it mean for the dialogue and deliberation or public engagement community to exclude social justice from its mission and activities? Many dialogue and deliberation organizations, though clearly not all, shy away from either an explicit or ...
Schoem, David
core  

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Public Deliberation in Health Policy and Bioethics: Mapping an emerging, interdisciplinary field

open access: yes, 2013
For over two decades, the deliberative turn has rooted itself in the fields of health policy and bioethics, producing a growing body of deliberation in action and associated academic scholarship.
Boesveld, Sarah E   +4 more
core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Beyond Deliberation: A Strategy for Civic Renewal

open access: yes, 2014
To expand opportunities for discussion and reflection about public issues, we should look beyond the organizations that intentionally convene deliberations and also enlist organizations that preserve common resources, volunteer service groups, civics ...
Levine, Peter
core  

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