Results 51 to 60 of about 84,725 (311)
Deliberación y decisión según Aristóteles
Tópicos, 2013 This paper argues that from Aristotle’s practical philosophy stem two different senses of προαίρεσις, which are related to two different senses of deliberation as well. The first sense of προαίρεσις refers to the particular deliberated choices, where the
Alejandro Vigo
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Learning as Abductive Deliberations [PDF]
, 2006 This paper explains an architecture for a BDI agent that can learn based on its own experience. The learning is conducted through explicit procedural knowledge or plans in a goal-directed manner. The learning is described by encoding abductions within the deliberation processes.
SUBAGDJA, Budhitama +2 more
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal of Deliberative Democracy, 2013 This paper examines the meanings of and distinctions between public deliberation and a tradition of participation in health committed to community empowerment, collective action, and social justice and their implications for health equity.
Erika Blacksher
doaj +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
International Journal of Communication, 2018 Deliberation researchers have started to question the commonly assumed association between democracy and deliberation, arguing that public deliberation in authoritarian regimes is not only theoretically possible, but also empirically existent.
Wenjie Yan
doaj
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source