Results 1 to 10 of about 216,498 (359)

Neurogranin in cerebrospinal fluid as a marker of synaptic dysfunction in hip fracture patients with delirium: a multicentre cross-sectional study [PDF]

BMJ Open
Objectives Neurogranin (Ng) has a role in synaptic plasticity and is considered a biomarker of synaptic dysfunction, a process hypothesised to be important in delirium. Few studies examining Ng in delirium exist, with mixed findings.
Henrik Zetterberg, Kaj Blennow, Dag Aarsland, Marius Myrstad, Mathias N P Hella, Nathalie B Halaas, Hogne Soennesyn, Anne K Bergland, Hanne B Hetland, Audun O Vik-Mo, Ane-Victoria Idland, Christian T Pollmann, Bjørn E Neerland, Leiv O Watne   +13 more
doaj   +2 more sources

Delirium in hip fracture patients admitted from home during the COVID-19 pandemic is associated with higher mortality, longer total length of stay, need for post-acute inpatient rehabilitation, and readmission to acute services: the IMPACT Delirium study

Bone & Joint Open, 2023
Aims: Delirium is associated with adverse outcomes following hip fracture, but the prevalence and significance of delirium for the prognosis and ongoing rehabilitation needs of patients admitted from home is less well studied.
Rose S. Penfold, Andrew J. Hall, Atul Anand, Nick D. Clement, Andrew D. Duckworth, Alasdair M. J. MacLullich   +5 more
doaj   +1 more source

Association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis

BMC Geriatrics, 2021
Background Delirium is a heterogeneous syndrome with inattention as the core feature. There is considerable variation in the presence and degree of other symptom domains such as altered arousal, psychotic features and global cognitive dysfunction ...
Zoë Tieges, Terence Quinn, Lorn MacKenzie, Daniel Davis, Graciela Muniz-Terrera, Alasdair M. J. MacLullich, Susan D. Shenkin   +6 more
doaj   +1 more source

Low Heart Rate Variability Predicts Stroke and Other Complications in the First Six Postoperative Months After a Hip Fracture Operation

Frontiers in Cardiovascular Medicine, 2021
Background: One-year mortality after hip fractures is underestimated and is reported as 25%. An improved risk stratifying could contribute to a better follow up of these patients. Heart Rate Variability (HRV) is an easy point-of-care investigation and is
Gernot Ernst, Gernot Ernst, Leiv Otto Watne, Leiv Otto Watne, Frede Frihagen, Frede Frihagen, Frede Frihagen, Torgeier Bruun Wyller, Torgeier Bruun Wyller, Andreas Dominik, Morten Rostrup, Morten Rostrup   +11 more
doaj   +1 more source

Use of Automated Infrared Pupillometry to Predict Delirium in the Intensive Care Unit: A Prospective Observational Study

SAGE Open Nursing, 2022
Introduction Delirium is an acute state of brain dysfunction prevalent among critically ill patients. Disturbances in the sympathetic neurons, including cholinergic neurons, have been reported to cause delirium by upsetting the balance of ...
Saiko Okamoto RN, MSN, Mihoko Ishizawa RN, PhD, Satoki Inoue MD, PhD, Hideaki Sakuramoto RN, PhD   +3 more
doaj   +1 more source

The frequency and quality of delirium documentation in discharge summaries

BMC Geriatrics, 2021
Background The National Institute for Health and Care Excellence recommends documenting all delirium episodes in the discharge summary using the term “delirium”. Previous studies demonstrate poor delirium documentation rates in discharge summaries and no
Victoria L Chuen, Adrian C.H Chan, Jin Ma, Shabbir M.H Alibhai, Vicky Chau   +4 more
doaj   +1 more source

Retrospective delirium ascertainment from case notes: a retrospective cohort study

BMJ Open, 2021
Objectives This study sets out to ascertain if recognition of delirium impacts on patient outcomes.Design Retrospective cohort study.Setting Unscheduled admissions to acute care trust/secondary care UK hospitals.Participants Six hundred and fifty-six ...
Qurrat Ul Ain, Lindsay Jones, Swetha Byravan, Joanne Taylor, Carly Welch, Lauren McCluskey, Fiona Herbert, Hussun-Ara Shah, Sarah Richardson, Thomas A Jackson, Gerry McGonigal, Benjamin Jelley, Jane Masoli, Christopher Miller, Daisy Wilson, Elizabeth Lonsdale-Eccles, Abigail Wrathall, Aidan Ryan, Al Wakkass Mahmood, Alexander Harbinson, Alice Wheeler, Amr Bazaraa, Amy Walter, Anekea Ross, Anna Reay, Chenxian Wu, Chioma Iwu, Dhruv Sarma, Elisabeth Hunter, Elizabeth J Ellis, Emily McNicholas, Fiona E Macdonald, Hannah J Robinson, Hannah Watson, Ijeoma T Obi, Imola Bargaoanu, James E Lucocq, Jane Giddings, Jenni Burton, Jodie Crofts, John Headlam, Kelli Torsney, Kumudhini Giridharan, Lahiru Satharasinghe, Laura J Beeley, Liji Ng, Mary Ni Lochlainn, Michael SJ Wilson, Minal D Patel, Mustafa Alsahab, Nader Nashed, Natalie Cox, Oliver Todd, Olivia Handley, Olugbenro Akintade, Philip Nwabufor, Philippa K Traill, Phillipa Adams, Rinata Farah, Robert Grange, Roisin Healy, Ruth Willott, Sarah Jagdeo, Shonit Nagumantry, Simon M Stapley, Sophie J Irwin, Sophie Wright, Srividya Sundara, Tarunya Vedutla, Thomas Arkle, Thyn Thyn, Vee-Han Lim, Victoria Gaunt, Yathu Matheswaran, Zeinab Majid   +74 more
doaj   +1 more source

The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses

BMC Pharmacology and Toxicology, 2018
Background The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium.
Karen Roksund Hov, Bjørn Erik Neerland, Anders Mikal Andersen, Øystein Undseth, Vegard Bruun Wyller, Alasdair M. J. MacLullich, Eva Skovlund, Eirik Qvigstad, Torgeir Bruun Wyller   +8 more
doaj   +1 more source

Diagnostic test accuracy of a novel smartphone application for the assessment of attention deficits in delirium in older hospitalised patients: a prospective cohort study protocol

BMC Geriatrics, 2018
Background Delirium is a common and serious clinical syndrome which is often missed in routine clinical care. The core cognitive feature is inattention.
Lisa-Marie Rutter, Eva Nouzova, David J. Stott, Christopher J. Weir, Valentina Assi, Jennifer H. Barnett, Caoimhe Clarke, Nikki Duncan, Jonathan Evans, Samantha Green, Kirsty Hendry, Meigan McGinlay, Jenny McKeever, Duncan G. Middleton, Stuart Parks, Robert Shaw, Elaine Tang, Tim Walsh, Alexander J. Weir, Elizabeth Wilson, Tara Quasim, Alasdair M.J. MacLullich, Zoë Tieges   +22 more
doaj   +1 more source

Current status of delirium assessment tools in the intensive care unit: a prospective multicenter observational survey

Scientific Reports, 2022
Delirium is a critical challenge in the intensive care unit (ICU) or high care unit (HCU) setting and is associated with poor outcomes. There is not much literature on how many patients in this setting are assessed for delirium and what tools are used ...
Kenzo Ishii, Kosuke Kuroda, Chika Tokura, Masaaki Michida, Kentaro Sugimoto, Tetsufumi Sato, Tomoki Ishikawa, Shingo Hagioka, Nobuki Manabe, Toshiaki Kurasako, Takashi Goto, Masakazu Kimura, Kazuharu Sunami, Kazuyoshi Inoue, Takashi Tsukiji, Takeshi Yasukawa, Satoshi Nogami, Mitsunori Tsukioki, Daisuke Okabe, Masaaki Tanino, Hiroshi Morimatsu   +20 more
doaj   +1 more source