Results 61 to 70 of about 216,498 (359)

Incremental medical cost of delirium in elderly patients with cognitive impairment: analysis of a nationwide administrative database in Japan

BMJ Open, 2022
Objectives Delirium is a neuropsychiatric disorder that commonly occurs in elderly patients with cognitive impairment. The economic burden of delirium in Japan has not been well characterised.
Shigeru Tokita, Kotoba Okuyama, Yasuyuki Okumura, Naoya Ueda, Masakazu Igarashi, Hideki Sano, Kanae Takahashi, Zaina P Qureshi, Asao Ogawa, Shoki Okuda   +9 more
doaj   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source

Incidence, Associated Factors, and Outcome of Delirium among Patients Admitted to ICUs in Oman

Critical Care Research and Practice, 2022
Background. The incidence of delirium is high up to 46.3% among patients admitted to ICU. Delirium is linked to negative patient outcomes like increased duration of mechanical ventilation use, prolonged ICU stay, increased mortality rate, and healthcare ...
Rasha Khamis Al-Hoodar, Eilean Rathinasamy Lazarus, Omar Al Omari, Omar Al Zaabi   +3 more
doaj   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

Advanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang, Zhi‐Xue Song, Si‐Ming Bu, Yi‐Mei Liu, Qing Li, Wen‐Xia Zhang, Xu‐Rong Sun, Xin Zhang, Yu‐Xuan Xiao, Di Bo, Xu‐Bin Miao, Chao Liu, Xin‐Hua Zhang, Lei Zheng, Hong‐Ye Zhao, Bao‐Lian Zhang, Wen Jia, Kui Chi, Yu Liu, Yong‐Bo Zhao, Bin Zheng, Dong Ma, Jin‐Kun Wen   +22 more
wiley   +1 more source

Delirium prevalence and management in general wards, emergency departments, rehabilitation centres and nursing homes in Germany, Austria and Switzerland (DACH countries): A secondary analysis of a worldwide point prevalence study

International Journal of Nursing Studies Advances
Background: Delirium is a common neuropsychiatric syndrome associated with an increased risk of mortality and length of stay. Current delirium prevalence, assessments and management practices of delirium in DACH countries are unknown.
Florian Schimböck, Lars Krüger, Magdalena Hoffmann, Marie-Madlen Jeitziner, Heidi Lindroth, Keibun Liu, Peter Nydahl, Rebecca Von Haken, Matthias Thomas Exl, Sibylle Fischbacher   +9 more
doaj   +1 more source

Data-driven categorization of postoperative delirium symptoms using unsupervised machine learning

Frontiers in Psychiatry, 2023
BackgroundPhenotyping analysis that includes time course is useful for understanding the mechanisms and clinical management of postoperative delirium. However, postoperative delirium has not been fully phenotyped.
Panyawut Sri-iesaranusorn, Ryoichi Sadahiro, Ryoichi Sadahiro, Syo Murakami, Saho Wada, Saho Wada, Ken Shimizu, Teruhiko Yoshida, Kazunori Aoki, Yasuhito Uezono, Hiromichi Matsuoka, Kazushi Ikeda, Junichiro Yoshimoto, Junichiro Yoshimoto   +13 more
doaj   +1 more source

Cognitive and mood assessment tools for use in stroke [PDF]

, 2018
No abstract ...
Elliott, Emma, Langhorne, Peter, Quinn, Terence J.   +2 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Combination of Ethoxybenzyl‐Diethylenetriamine Pentaacetic Acid‐Enhanced Magnetic Resonance Imaging and a Serum Biomarker Is Useful in the Diagnosis of Hepatic Sinusoidal Disorder After Chemotherapy Treatment

Annals of Gastroenterological Surgery, EarlyView.
ROC analyses of APRI score, EOB‐MRI, and a combination of EOB‐MRI and APRI score for blue liver. ABSTRACT Aim Sinusoidal obstruction syndrome (SOS), also known as “blue liver (BL),” is a common hepatic injury following oxaliplatin‐based chemotherapy in patients with colorectal liver metastases (CRLM).
Tomonari Shimagaki, Keishi Sugimachi, Takahiro Tomino, Takeshi Kurihara, Emi Onishi, Yutaro Shimomura, Kenji Shinozaki, Masaru Morita   +7 more
wiley   +1 more source

Delirium in geriatric patients with hip fracture

Neurologijos seminarai, 2021
ntroduction. Delirium occurs in up to 87% of the intensive care unit (ICU) patients and is associated with numerous poor outcomes. The drug most commonly used to treat delirium is haloperidol, a centrally acting dopamine antagonist.
A. Konkayev , N. Bekmagambetova, M. Konkayeva, M. Šerpytis , D. Gineitytė-Ozolince, J. Šipylaitė , D. Jatužis   +6 more
doaj   +1 more source