Results 231 to 240 of about 17,143 (248)
Some of the next articles are maybe not open access.
Activity of delphinidin on microvascular damage models in rodents
Phytotherapy Research, 1992AbstractDelphinidin chloride (IdB 1056) was found to possess a significant activity by the intraperitoneal and oral routes in different experimental models of microvascular damage. It antagonized the increase in skin capillary permeability induced by histamine in rats and rabbits, by bradykinin and hyaluronidase in rats and by xylol in mice ...
M. Conti, A. Cristoni, M. J. Magistretti
openaire +1 more source
Journal of Biomolecular Structure and Dynamics, 2005
Flavonoids are strong antioxidants that prevent DNA damage. The anticancer and antiviral activities of these natural products are implicated in their mechanism of actions. However, there has been no information on the interactions of these antioxidants with individual DNA at molecular level.
C D, Kanakis +4 more
openaire +2 more sources
Flavonoids are strong antioxidants that prevent DNA damage. The anticancer and antiviral activities of these natural products are implicated in their mechanism of actions. However, there has been no information on the interactions of these antioxidants with individual DNA at molecular level.
C D, Kanakis +4 more
openaire +2 more sources
Blockade of the Renin-Angiotensin System with Delphinidin, Cyanin, and Quercetin
Planta Medica, 2012Overactivation of the renin-angiotensin system is one of the most important risk factors for the development of hypertension. The use of the crude extracts and/or active compounds, such as anthocyanins and quercetin, of herbal plants that have antihypertensive effects is beneficial for decreasing of blood pressure level.
Warisara, Parichatikanond +2 more
openaire +2 more sources
Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I
Bioorganic & Medicinal Chemistry, 2010Glyoxalase I (GLO I) is the rate-limiting enzyme for detoxification of methylglyoxal (MG), a side-product of glycolysis, which is able to induce apoptosis. Since GLO I is known to be highly expressed in the most tumor cells and little in normal cells, inhibitors of this enzyme has been expected to be new anticancer drugs.
Ryoko, Takasawa +6 more
openaire +2 more sources
Effects of the natural flavonoid delphinidin on diabetic microangiopathy.
Arzneimittel-Forschung, 1995The purpose of the present study was to investigate the effects of the flavonoid delphinidin chloride (CAS 528-53-0, IdB 1056) on diabetic microangiopathy. Hamsters were injected with alloxan and cheek pouch microcirculation was observed by a fluorescent microscopy technique 90 days from alloxan.
BERTUGLIA S. +2 more
openaire +3 more sources
Delphinidin 3′-galloylgalactosides from blue flowers of Nymphaéa caerulea
Phytochemistry, 1999Abstract Two novel acylated anthocyanins have been isolated from blue flowers of the African water lily Nympha ea caerulea (= Nympha ea capensis). By a combination of chromatography, electrospray MS and homo- and heteronuclear two-dimensional NMR techniques they were identified to be delphinidin 3′- O - (2″- O -galloyl- β -galactopyranoside) (1) and
Torgils Fossen, Øyvind M Andersen
openaire +1 more source
Acylated delphinidin glycosides in the blue-violet flowers of Consolida armeniaca
Phytochemistry, 1996Four new acylated delphinidin 3,7-glycosides were isolated from the blue-violet flowers of Consolida armeniaca as major anthocyanin pigments. The first pigment was based on delphinidin 3,7-diglucoside and was identified as delphinidin 3-O-[6-O-(malonyl)-beta-D-glucopyranoside]-7-O- [6-O-(4-O-(6-O-(p-hydroxybenzoyl)-beta-D-glucopyranosyl)-p ...
N, Saito, K, Toki, S, Ozden, T, Honda
openaire +2 more sources
Abstract 4133: Hyaluronidase inhibitor delphinidin inhibits cancer metastasis
Cancer ResearchAbstract Cancer remains a formidable global health challenge, with metastasis being a key contributor to its lethality. Abundant high molecular weight hyaluronic acid, a major non-protein component of extracellular matrix, protects naked mole rats from cancer and reduces cancer incidence in mice.
Jeremy Jonathan McGuire +7 more
openaire +1 more source
Toxicology, 2010
The aim of this study was to investigate the hepatoprotective effects of anthocyanidin delphinidin in carbon tetrachloride (CCl(4))-induced liver fibrosis in mice. Male Balb/C mice were treated with CCl(4) dissolved in olive oil (20%, v/v, 2mL/kg) intraperitoneally (i.p.), twice a week for 7 weeks. Delphinidin was administered i.p.
Domitrović, Robert, Jakovac, Hrvoje
openaire +3 more sources
The aim of this study was to investigate the hepatoprotective effects of anthocyanidin delphinidin in carbon tetrachloride (CCl(4))-induced liver fibrosis in mice. Male Balb/C mice were treated with CCl(4) dissolved in olive oil (20%, v/v, 2mL/kg) intraperitoneally (i.p.), twice a week for 7 weeks. Delphinidin was administered i.p.
Domitrović, Robert, Jakovac, Hrvoje
openaire +3 more sources
Delphinidin inhibits BDNF-induced migration and invasion in SKOV3 ovarian cancer cells
Bioorganic & Medicinal Chemistry Letters, 2017Brain-derived neurotrophic factor (BDNF), the TrkB ligand, is associated with aggressive malignant behavior, including migration and invasion, in tumor cells and a poor prognosis in patients with various types of cancer. Delphinidin is a diphenylpropane-based polyphenolic ring structure-harboring compound, which exhibits a wide range of pharmacological
Won-Chul Lim +10 more
openaire +2 more sources