Results 11 to 20 of about 4,018 (187)

Pathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs [PDF]

Emerging Infectious Diseases, 2015
To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs.
Kwonil Jung, Hui Hu, Bryan Eyerly, Zhongyan Lu, Juliet Chepngeno, Linda J. Saif   +5 more
doaj   +4 more sources

The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals

Viruses, 2022
The existing zoonotic coronaviruses (CoVs) and viral genetic variants are important microbiological pathogens that cause severe disease in humans and animals.
Fenghua Wang, Cheng Chen, Zefang Wang, Xu Han, Peidian Shi, Kaixuan Zhou, Xiaomei Liu, Yunjie Xiao, Yan Cai, Jinhai Huang, Lei Zhang, Haitao Yang   +11 more
doaj   +2 more sources

Detection and Genetic Characterization of Deltacoronavirus in Pigs, Ohio, USA, 2014

Emerging Infectious Diseases, 2014
In Ohio, United States, in early 2014, a deltacoronavirus was detected in feces and intestine samples from pigs with diarrheal disease. The complete genome sequence and phylogenetic analysis of the virus confirmed that the virus is closely related to a ...
Leyi Wang, Beverly Byrum, Yan Zhang
doaj   +2 more sources

Gammacoronavirus and Deltacoronavirus in Quail

Avian Diseases, 2016
This paper expands a previous report on coronavirus in quail. To this end, samples were collected from São Paulo state, Southeastern Brazil, in 2013, when some farmers started quail vaccination with Massachusetts IBV serotype after surveillance carried ...
Taniwaki, S. A., Brandão, P. E., CECCHINATO, MATTIA, Villarreal, L. Y. B., Hora, A. S., Torres, C. A., Tonietti, P. O.   +6 more
core   +3 more sources

Structures of a deltacoronavirus spike protein bound to porcine and human receptors

Nature Communications, 2022
Porcine deltacoronavirus (PDCoV) can experimentally infect a variety of animals. Human infection by PDCoV has also been reported. Consistently, PDCoV can use aminopeptidase N (APN) from different host species as receptors to enter cells.
Weiwei Ji, Qi Peng, Xueqiong Fang, Zehou Li, Yaxin Li, Cunfa Xu, Shuqing Zhao, Jizong Li, Rong Chen, Guoxiang Mo, Zhanyong Wei, Ying Xu, Bin Li, Shuijun Zhang   +13 more
doaj   +2 more sources

Antiviral Effect of Lithium Chloride and Diammonium Glycyrrhizinate on Porcine Deltacoronavirus In Vitro

Pathogens, 2019
Porcine deltacoronavirus (PDCoV) is an emerging global swine virus that has a propensity for interspecies transmission. It was identified in Hong Kong in 2012.
Xiaofeng Zhai, Shilei Wang, Mengyan Zhu, Wei He, Zhongzhou Pan, Shuo Su   +5 more
doaj   +2 more sources

The N-terminal Subunit of the Porcine Deltacoronavirus Spike Recombinant Protein (S1) Does Not Serologically Cross-react with Other Porcine Coronaviruses

Pathogens, 2022
Porcine deltacoronavirus (PDCoV), belonging to family Coronaviridae and genus Deltacoronavirus, is a major enteric pathogen in swine. Accurate PDCoV diagnosis relying on laboratory testing and antibody detection is an important approach.
Lu Yen, Ronaldo Magtoto, Juan Carlos Mora-Díaz, Jose Antonio Carrillo-Ávila, Jianqiang Zhang, Ting-Yu Cheng, Precy Magtoto, Rahul K. Nelli, David H. Baum, Jeffrey J. Zimmerman, Luis G. Giménez-Lirola   +10 more
doaj   +2 more sources

Rapid Detection, Complete Genome Sequencing, and Phylogenetic Analysis of Porcine Deltacoronavirus

Emerging Infectious Diseases, 2014
In February 2014, porcine deltacoronavirus (PDCoV) was identified in the United States. We developed a PDCoV real-time reverse transcription PCR that identified PDCoV in 30% of samples tested.
Douglas Marthaler, Lindsey Raymond, Yin Jiang, James Collins, Kurt Rossow, Albert Rovira   +5 more
doaj   +2 more sources

Characteristics of the Life Cycle of Porcine Deltacoronavirus (PDCoV) In Vitro: Replication Kinetics, Cellular Ultrastructure and Virion Morphology, and Evidence of Inducing Autophagy

Viruses, 2019
Porcine deltacoronavirus (PDCoV) causes severe diarrhea and vomiting in affected piglets. The aim of this study was to establish the basic, in vitro characteristics of the life cycle such as replication kinetics, cellular ultrastructure, virion ...
Pan Qin, En-Zhong Du, Wen-Ting Luo, Yong-Le Yang, Yu-Qi Zhang, Bin Wang, Yao-Wei Huang   +6 more
doaj   +2 more sources

Susceptibility of Cell Lines from Different Species to Porcine Deltacoronavirus. [PDF]

Viruses
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes severe diarrhea in piglets, leading to extensive economic losses in the global swine industry.
Jiang H, Lu B, Chu Y, Ma M, Zhang N, Xu Y, Chen Y, Xiao Q, Wang T, Peng Q.   +9 more
europepmc   +5 more sources