Results 41 to 50 of about 4,018 (187)

Assessment of hemagglutination activity of porcine deltacoronavirus

Journal of Veterinary Science, 2020
Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated.
Yunfei Zhang, Li Han, Lu Xia, Yixin Yuan, Hui Hu   +4 more
openaire   +2 more sources

Genomic Epidemiology, Evolution, and Transmission Dynamics of Porcine Deltacoronavirus [PDF]

Molecular Biology and Evolution, 2020
Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown once again that coronavirus (CoV) in animals are potential sources for epidemics in humans. Porcine deltacoronavirus (PDCoV) is an emerging enteropathogen of swine with a worldwide distribution.
He, Wan-Ting, Ji, Xiang, He, Wei, Dellicour, Simon, Wang, Shilei, Li, Gairu, Zhang, Letian, Gilbert, Marius, Zhu, Henan, Xing, Gang, Veit, Michael, Huang, Zhen, Han, Guan-Zhu, Huang, Yaowei, Suchard, Marc A., Baele, Guy, Lemey, Philippe, Su, Shuo   +17 more
openaire   +6 more sources

Independent infections of porcine deltacoronavirus among Haitian children [PDF]

Nature, 2021
Abstract Coronaviruses have caused three major epidemics since 2003, including the ongoing SARS-CoV-2 pandemic. In each case, the emergence of coronavirus in our species has been associated with zoonotic transmissions from animal reservoirs 1,2 , underscoring how prone such ...
John A. Lednicky, Massimiliano S. Tagliamonte, Sarah K. White, Maha A. Elbadry, Md. Mahbubul Alam, Caroline J. Stephenson, Tania S. Bonny, Julia C. Loeb, Taina Telisma, Sonese Chavannes, David A. Ostrov, Carla Mavian, Valery Madsen Beau De Rochars, Marco Salemi, J. Glenn Morris   +14 more
openaire   +2 more sources

Porcine deltacoronavirus: histological lesions and genetic characterization [PDF]

Archives of Virology, 2015
First identified in 2012 in a surveillance study in Hong Kong, porcine deltacoronavirus (PDCoV) is a proposed member of the genus Deltacoronavirus of the family Coronaviridae. In February of 2014, PDCoV was detected in pigs with clinical diarrheal symptoms for the first time in the USA. Since then, it has been detected in more than 20 states in the USA
Wang, Leyi, Hayes, Jeff, Sarver, Craig, Byrum, Beverly, Zhang, Yan   +4 more
openaire   +2 more sources

RNA G-Quadruplexes in the Porcine Deltacoronavirus Genome: Structural Regulation and Therapeutic Targeting for Antiviral Strategies. [PDF]

Transbound Emerg Dis
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that poses a considerable risk to swine production worldwide. G‐quadruplexes (G4s) are noncanonical nucleic acid secondary structures known to regulate critical steps of viral life cycles in multiple viruses; however, the existence and biological role of RNA G4s (RG4s) in PDCoV remain ...
Guo J, Yu M, Sun Y, Chen Q, Liu F, Shan Y.   +5 more
europepmc   +2 more sources

Porcine Deltacoronavirus Nsp13 Suppresses the Assembly of the MAVS-TBK1-IRF3 Complex and IRF9 Nuclear Translocation. [PDF]

Transbound Emerg Dis
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that causes substantial morbidity in swine and may pose a zoonotic risk because of its cross‐species transmission potential. Type I interferon (IFN‐I) signaling is central to antiviral defense, initiated through the mitochondrial antiviral signaling (MAVS)–TBK1–IFN regulatory factor 3 (
Wang Y, Lan S, Fang Z, Yang S, Wang X, Shen Q, Liu Y, Wu P, Zhou C, Zhang W, Ji L.   +10 more
europepmc   +2 more sources

Cholesterol is important for the entry process of porcine deltacoronavirus [PDF]

Archives of Virology, 2018
The present study was conducted to examine whether cellular and/or viral cholesterol levels play a role in porcine deltacoronavirus (PDCoV) replication. Our results showed that depletion of cholesterol from cells or virions by treating them with methyl-β-cyclodextrin (MβCD) diminished PDCoV infection in a dose-dependent manner.
Ji Hyun Jeon, Changhee Lee
openaire   +2 more sources

Characterization of the Cross-Species Transmission Potential for Porcine Deltacoronaviruses Expressing Sparrow Coronavirus Spike Protein in Commercial Poultry

Viruses, 2022
Avian species often serve as transmission vectors and sources of recombination for viral infections due to their ability to travel vast distances and their gregarious behaviors. Recently a novel deltacoronavirus (DCoV) was identified in sparrows. Sparrow
Moyasar A. Alhamo, Patricia A. Boley, Mingde Liu, Xiaoyu Niu, Kush Kumar Yadav, Carolyn Lee, Linda J. Saif, Qiuhong Wang, Scott P. Kenney   +8 more
doaj   +1 more source

Porcine deltacoronavirus infection is inhibited by Griffithsin in cell culture

Veterinary Microbiology, 2022
Porcine deltacoronavirus (PDCoV) is an emerging porcine enteric coronavirus that causes severe diarrhea in piglets and results in serious economic losses. There are no effective vaccines and antiviral drugs to prevent and treat PDCoV infection currently.
Rongfeng Tang, Longjun Guo, Qianjin Fan, Liaoyuan Zhang, Yiming Wang, Xin Zhang, Da Shi, Yang Wu, Hongyan Shi, Jianbo Liu, Jianfei Chen, Li Feng   +11 more
openaire   +2 more sources

An Updated Review of Porcine Deltacoronavirus in Terms of Prevalence, Pathogenicity, Pathogenesis and Antiviral Strategy

Frontiers in Veterinary Science, 2022
The recent experience with SARS-COV-2 has raised our alarm about the cross-species transmissibility of coronaviruses and the emergence of new coronaviruses. Knowledge of this family of viruses needs to be constantly updated.
Cong Duan
doaj   +1 more source