Results 31 to 40 of about 4,018 (187)
Inhibition of porcine deltacoronavirus entry and replication by Cepharanthine
Virus Research, 2023 Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus (CoV) that mainly causes acute diarrhea/vomiting, dehydration, and mortality in piglets, possessing economic losses and public health concerns.
Yumei Sun +8 more
doaj +3 more sources
PEX19 restricts porcine deltacoronavirus replication through farnesylation-dependent and -independent mechanisms [PDF]
Journal of VirologyPeroxisomes are vital cellular organelles that play critical roles in metabolism, immune regulation, and disease pathogenesis. As a key receptor for peroxisomal membrane proteins, peroxisomal biogenesis factor 19 (PEX19) is essential for peroxisome ...
Chaoqun Chen +8 more
doaj +2 more sources
CRISPR/Cas13a-based rapid detection method for porcine deltacoronavirus
Frontiers in MicrobiologyBackgroundPorcine deltacoronavirus (PDCoV) is a newly discovered porcine intestinal pathogenic coronavirus with a single-stranded positive-sense RNA genome and an envelope.
Ran Luo +11 more
doaj +3 more sources
A Previously Undiscovered Circular RNA, circTNFAIP3, and Its Role in Coronavirus Replication
mBio, 2021 Circular RNAs (circRNAs) are a newly discovered class of noncoding RNAs (ncRNAs) present in various tissues and cells. However, the functions of most circRNAs have not been verified experimentally.
Liuyang Du +7 more
doaj +1 more source
Viruses, 2022 This study characterized the susceptibility and dynamic of porcine deltacoronavirus infection in grower pigs under experimental conditions using a combination of syndromic and laboratory assessments.
Lu Yen +10 more
doaj +1 more source
Multiplex Real-Time RT-PCR Assays for Detection and Differentiation of Porcine Enteric Coronaviruses
Pathogens, 2023 It is important to be able to detect and differentiate between distinct porcine enteric coronaviruses that can cause similar diseases. However, the existence of naturally occurring recombinant coronaviruses such as swine enteric coronavirus (SeCoV) can ...
Christina M. Lazov +5 more
doaj +1 more source
Frontiers in Microbiology, 2022 Deltacoronavirus (DCoV) is a genus of coronavirus (CoV) commonly found in avian and swine, but some DCoVs are capable of infecting humans, which causes the concern about interspecies transmission of DCoVs.
Kan-Kan Chu +8 more
doaj +1 more source
Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31. [PDF]
Adv Sci (Weinh)Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Hou J +11 more
europepmc +2 more sources
Subcellular localization of the porcine deltacoronavirus nucleocapsid protein [PDF]
Virus Genes, 2020 Porcine deltacoronavirus (PDCoV) has been recently identified as an emerging enteropathogenic coronavirus that mainly infects newborn piglets and causes enteritis, diarrhea and high mortality. Although coronavirus N proteins have multifarious activities, the subcellular localization of the PDCoV N protein is still unknown.
Zhen Ding +12 more
openaire +2 more sources
A novel strain of porcine deltacoronavirus in Vietnam [PDF]
Archives of Virology, 2017 Two porcine deltacoronavirus (PDCoV) strains (Binh21 and HaNoi6) were isolated from two pig farms in North Vietnam. Phylogenetic analysis of the complete genomes and the Spike and Membrane genes revealed that the two Vietnam PDCoVs belong to the same lineage as PDCoVs from Thailand and Laos; however, the N genes belonged to the same lineage as PDCoVs ...
Le, Van Phan +10 more
openaire +2 more sources