Results 1 to 10 of about 1,388 (138)
Abstract Aim In the United Kingdom, organ donors/recipients are screened for evidence of human T‐cell leukaemia virus type‐1 and type‐2 (HTLV‐1/2) infections. Since the United Kingdom is a low prevalence country for HTLV infections, a screening assay with high sensitivity and specificity is required.
Nathaniel Lee+8 more
wiley +1 more source
Abstract Propolis is a complex natural product that possesses antioxidant, anti‐inflammatory, immunomodulatory, antibacterial, and antiviral properties mainly attributed to the high content in flavonoids, phenolic acids, and their derivatives. The chemical composition of propolis is multifarious, as it depends on the botanical sources from which ...
Andrea Magnavacca+3 more
wiley +1 more source
As genetically resistant individuals, the “elite controllers” (ECs) of human immunodeficiency virus infection have been focused on as the keys to developing further functional treatments in medicine. In the livestock production field, identifying the ECs of bovine leukemia virus (BLV) infection in cattle is desired to stop BLV transmission chains on ...
Kosuke Notsu+4 more
wiley +1 more source
Human T‐cell leukemia virus type 1‐ (HTLV‐1‐) associated arthritis is a relatively common disease. However, tenosynovitis owing to adult T‐cell leukemia‐lymphoma (ATL) is a rare condition. To the best of our knowledge, there have been no reports of tenosynovitis caused by conversion to acute ATL from one of the other ATL types. We present the case of a
Akira Hashimoto+5 more
wiley +1 more source
First Report of Bovine Leukemia Virus Infection in Yaks (Bos mutus) in China
Enzootic bovine leukosis (EBL) is a chronic lymphosarcoma disease of cattle caused by bovine leukemia virus (BLV). No information is available concerning the epidemiology of BLV infection in yaks (Bos mutus). One thousand five hundred and eighty‐four serum samples from 610 black yaks and 974 white yaks from Gansu province, northwest China, were ...
Jian-Gang Ma+7 more
wiley +1 more source
Automatic Generation of Validated Specific Epitope Sets
Accurate measurement of B and T cell responses is a valuable tool to study autoimmunity, allergies, immunity to pathogens, and host‐pathogen interactions and assist in the design and evaluation of T cell vaccines and immunotherapies. In this context, it is desirable to elucidate a method to select validated reference sets of epitopes to allow detection
Sebastian Carrasco Pro+7 more
wiley +1 more source
The present study investigated the association between the rs12979860 polymorphism in the IL‐28B gene and HTLV‐1 infection as well as the development of HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV‐1‐infected patients (26 HAM/TSP symptomatic and 53 asymptomatic) and 300 seronegative healthy controls were investigated ...
Antonio C. R. Vallinoto+10 more
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The Role of Cytidine Deaminases on Innate Immune Responses against Human Viral Infections
The APOBEC family of proteins comprises deaminase enzymes that edit DNA and/or RNA sequences. The APOBEC3 subgroup plays an important role on the innate immune system, acting on host defense against exogenous viruses and endogenous retroelements. The role of APOBEC3 proteins in the inhibition of viral infection was firstly described for HIV‐1. However,
Valdimara C. Vieira+2 more
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Complex Codon Usage Pattern and Compositional Features of Retroviruses
Retroviruses infect a wide range of organisms including humans. Among them, HIV‐1, which causes AIDS, has now become a major threat for world health. Some of these viruses are also potential gene transfer vectors. In this study, the patterns of synonymous codon usage in retroviruses have been studied through multivariate statistical methods on ORFs ...
Sourav RoyChoudhury+2 more
wiley +1 more source
Human T‐cell leukemia virus type‐1 (HTLV‐1) is a replication‐competent human retrovirus associated with two distinct types of disease only in a minority of infected individuals: the malignancy known as adult T‐cell leukemia (ATL) and a chronic inflammatory central nervous system disease HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Mineki Saito+2 more
wiley +1 more source