Results 21 to 30 of about 1,809 (167)
Retrovirology, 2007 Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hoelzer Dieter +4 more
doaj +2 more sources
Early and transient reverse transcription during primary deltaretroviral infection of sheep [PDF]
Retrovirology, 2008 Background Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has only been investigated during the chronic phase of the
Wattel Eric +7 more
doaj +2 more sources
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ [PDF]
Nature Communications, 2020 Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Michał S. Barski +6 more
doaj +3 more sources
Retrovirology, 2007 In 1871, the observation of yellowish nodules in the enlarged spleen of a cow was considered to be the first reported case of bovine leukemia. The etiological agent of this lymphoproliferative disease, bovine leukemia virus (BLV), belongs to the ...
Burny Arsène +12 more
doaj +2 more sources
Post-transcriptional Regulation of HTLV Gene Expression: Rex to the Rescue [PDF]
Frontiers in Microbiology, 2019 Human T-lymphotropic virus type 1 (HTLV-1) and other members of the Deltaretrovirus genus code for a regulatory protein named Rex that binds to the Rex-responsive element present on viral mRNAs.
Donna M. D’Agostino +4 more
doaj +4 more sources
Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective
Viruses, 2021 Bovine leukaemia virus (BLV) is a deltaretrovirus that is closely related to human T-cell leukaemia virus types 1 and 2 (HTLV-1 and -2). It causes enzootic bovine leukosis (EBL), which is the most important neoplastic disease in cattle. Most BLV-infected
Marawan A. Marawan +9 more
doaj +2 more sources
Recent Advances in BLV Research [PDF]
Viruses, 2015 Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and macaques.
Pierre-Yves Barez +14 more
doaj +2 more sources
Definitions, 2020 the family retroviridae consisting of exogenous horizontally transmitted viruses found in mammals; associated with B or T cell leukemia/lymphoma ...
openaire +2 more sources
Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice [PDF]
Nature Structural & Molecular BiologyHuman T cell leukemia virus type 1 (HTLV-1) immature particles differ in morphology from other retroviruses, suggesting a distinct way of assembly. Here we report the results of cryo-electron tomography studies of HTLV-1 virus-like particles assembled in
Percipalle, Mathias +9 more
core +2 more sources
Bovine Leukemia Virus DNA in Human Breast Tissue [PDF]
Emerging Infectious Diseases, 2014 Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring +5 more
doaj +2 more sources