Results 11 to 20 of about 1,809 (167)

Human T-Lymphotropic Viruses Evolution Possibly Explained by Primate Deltaretrovirus Geographical Segregation [PDF]

Retrovirology: Research and Treatment, 2008
The primate T cell lymphotropic virus group comprises pathogenic and apathogenic agents found in human and simian hosts. Up to date, three types of the simian T cell lymphotropic virus/STLV and four types of the human T cell lymphotropic virus/HTLV have been isolated and characterized from non human primates and from human hosts respectively.
Casseb, Jorge Simão do Rosário, Kanzaki, Luis Isamu Barros   +1 more
core   +5 more sources

Epidemiology and genetic diversity of bovine leukemia virus

Virology Journal, 2017
Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses.
Meripet Polat, Shin-nosuke Takeshima, Yoko Aida   +2 more
doaj   +3 more sources

Cytokine secretion in stem cells of cattle infected with bovine leukaemia virus

Journal of Veterinary Research
Bovine leukaemia virus (BLV) is a Deltaretrovirus responsible for enzootic bovine leukosis, the most common neoplastic disease of cattle. It deregulates the immune system, favouring secondary infections and changes in the blood and lymphatic tissues ...
Szczotka Maria, Kuźmak Jacek
doaj   +3 more sources

Phylogenetic Analysis of Amino Acid Sequences of Regulatory Protein Tax of Bovine Leukemia Virus and Other Deltaretrovirus

Veterinaria I Kormlenie, 2019
I.M. Zyrianova, S.N. Koval'chuk
exaly   +3 more sources

Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]

Anim Genet
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM, Farjami Z, Murillo CR, González-Fernández VD, Acevedo-Jiménez GE, de María Ávila-De la Vega L, Álvarez HR.   +6 more
europepmc   +3 more sources

Expression of integrins β1, α4 and cell adhesion molecule ICAM-1 in the presence of sodium deoxyribonucleate with ferrum complex (DNA-Na-Fe) by MT-4 cells transformed by human T-lymphotropic virus type 1 (Retroviridae: Orthoretrovirinae: Deltaretrovirus: Human T-lymphotropic virus type 1)

Problems of Virology, 2021
Introduction. The important role of integrins (IG) in the initiation and development of cancer processes makes these structures convenient targets for the development of immunomodulatory therapeutic drugs that have an effect directly on these molecules.
L. B. Kalnina, L. M. Selimova, E. N. Kaplina, D. N. Nosik   +3 more
openaire   +5 more sources

Strengthening awareness and response to HTLV-1 infection in Africa: A neglected threat to blood safety and public health. [PDF]

Hemasphere
HemaSphere, Volume 9, Issue 10, October 2025.
Twizere JC, Rosadas C, Kidiga M, Djalo F, Murphy EL, Mouinga-Ondeme A, Vermeulen M, Morrell L, Diop S, Maseko S, Sebulime P, Agbleke AA, Fundisi B, Umumararungu E, Watber P, Hlela C, Nhavene E, Chidarikire T, Hermine O, Gessain A.   +19 more
europepmc   +3 more sources

Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species [PDF]

Retrovirology, 2019
The Deltaretrovirus genus of retroviruses (family Retroviridae) includes the human T cell leukemia viruses and bovine leukemia virus (BLV). Relatively little is known about the biology and evolution of these viruses, because only a few species have been ...
Tomáš Hron, Daniel Elleder, Robert J. Gifford   +2 more
doaj   +2 more sources

Different Mutation Tolerance of Lentiviral (HIV-1) and Deltaretroviral (BLV and HTLV) Protease Precursors

Viruses, 2022
The bovine leukemia virus (BLV) and the human T-lymphothropic viruses (HTLVs) are members of the deltaretrovirus genus of Retroviridae family. An essential event of the retroviral life cycle is the processing of the polyproteins by the viral protease (PR)
János András Mótyán, Norbert Kassay, Krisztina Matúz, József Tőzsér   +3 more
doaj   +2 more sources

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures [PDF]

Nature Communications, 2021
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Michal S. Barski, Teresa Vanzo, Xue Zhi Zhao, Steven J. Smith, Allison Ballandras-Colas, Nora B. Cronin, Valerie E. Pye, Stephen H. Hughes, Terrence R. Burke, Peter Cherepanov, Goedele N. Maertens   +10 more
doaj   +3 more sources