Capture in the metabolic arena: co-selection of gamma and deltaretrovirus envelope glycoproteins and their receptors [PDF]
Although all infectious and replication-competent retroviruses harbor an env gene, the origin of env remains unknown except for that of a few invertebrate retroviruses. It is generally admitted that infectious retroviruses have evolved from endogenous viral retrotransposons by insertion of an ''external'' gene that encodes for a fusion glycoprotein ...
Nicolas Manel +2 more
exaly +4 more sources
North American Big Brown Bats (
Bats are the reservoir for a large number of zoonotic viruses, including members of Coronaviridae (severe acute respiratory syndrome coronavirus [SARS-CoV] and SARS-CoV-2), Paramyxoviridae (Hendra and Nipah viruses), Rhabdoviridae (rabies virus), and ...
Ben M. Hause +2 more
doaj +3 more sources
Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM +6 more
europepmc +2 more sources
Comparison of the Prevalence of Bovine Leukemia Virus (BLV) in Holstein and Angus Cattle Breeds From Shandong Province, China. [PDF]
ABSTRACT Bovine leukemia virus (BLV) is widespread globally and causes economic losses in the cattle industry. Shandong Province plays a significant role in China's livestock industry, with an increasing importance in food of Holstein and Angus cattle. However, BLV prevalence in Holstein and Angus breeds in Shandong Province remains unclear.
Wang J +13 more
europepmc +2 more sources
Milk Macrophage Function in Bovine Leukemia Virus-Infected Dairy Cows
The implications of bovine leukemia virus (BLV) on innate and adaptive immune responses have been widely investigated; however, the effects of BLV on mammary gland immunity require further investigation.
Ewerton de Souza Lima +16 more
doaj +1 more source
Impact of BoLA-DRB3 Polymorphisms on Clonality of Bovine Leukaemia Virus-Infected Cells of Cattle With Lymphoma. [PDF]
ABSTRACT Bovine leukaemia virus (BLV) infects cattle, integrates into the host genome as a provirus, and induces a persistent infection that remains asymptomatic but can cause leukaemia/lymphoma. Most BLV‐infected cell clones are created by massive depletion, and a few of these infected cell clones expand through the mitotic cycle, leading to the onset
Fukushi N +10 more
europepmc +2 more sources
Human T-lymphotropic virus 1 (HTLV-1) is the etiologic agent of adult cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Debora Glenda Lima de La-Roque +9 more
doaj +1 more source
Strengthening awareness and response to HTLV-1 infection in Africa: A neglected threat to blood safety and public health. [PDF]
HemaSphere, Volume 9, Issue 10, October 2025.
Twizere JC +19 more
europepmc +2 more sources
Introduction. The important role of integrins (IG) in the initiation and development of cancer processes makes these structures convenient targets for the development of immunomodulatory therapeutic drugs that have an effect directly on these molecules.
L. B. Kalnina +3 more
openaire +4 more sources
Protease-mediated maturation of M-PMV reverse transcriptase into a functional heterodimer. [PDF]
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Kapisheva M +6 more
europepmc +2 more sources

