Early and transient reverse transcription during primary deltaretroviral infection of sheep [PDF]
Retrovirology, 2008 Background Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has only been investigated during the chronic phase of the
Wattel Eric +7 more
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Molecular Studies of HTLV-1 Replication: An Update
Viruses, 2016 Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered. Studies on HTLV-1 have been instrumental for our understanding of the molecular pathology of virus-induced cancers.
Joachim D. Mueller +2 more
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Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human [PDF]
Retrovirology, 2007 In 1871, the observation of yellowish nodules in the enlarged spleen of a cow was considered to be the first reported case of bovine leukemia. The etiological agent of this lymphoproliferative disease, bovine leukemia virus (BLV), belongs to the ...
Burny Arsène +12 more
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Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ [PDF]
Nature Communications, 2020 Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.
Michał S. Barski +6 more
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Engineered soluble truncated envelope proteins block bovine leukemia virus infection [PDF]
Virus ResearchBovine leukemia virus (BLV), a member of the delta retrovirus family, is transmitted horizontally among cows. BLV causes enzootic bovine leukosis and has great economic impact on the cattle industry.
Nashon Wanjala +4 more
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Detection of Bovine Leukemia Virus in Bone Marrow of Patients with B-Cell Precursor Acute Lymphoblastic Leukemia: A Case–Control Study [PDF]
VirusesBovine leukemia virus (BLV) is an oncogenic deltaretrovirus that infects B cells, and its possible presence in humans has garnered increasing attention.
Kerlimber Núñez-Gutiérrez +4 more
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Post-transcriptional Regulation of HTLV Gene Expression: Rex to the Rescue [PDF]
Frontiers in Microbiology, 2019 Human T-lymphotropic virus type 1 (HTLV-1) and other members of the Deltaretrovirus genus code for a regulatory protein named Rex that binds to the Rex-responsive element present on viral mRNAs.
Donna M. D’Agostino +4 more
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Prevalence of human T-cell lymphotropic virus in blood donor screening at the Blood Center: a descriptive study, Mato Grosso, 2018-2021 [PDF]
Epidemiologia e Serviços de SaúdeObjectives: To describe the prevalence of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) infection among blood donors at the Mato Grosso Blood Center between January 2018 and August 2021, as well as to report the demographic characteristics and ...
Pennsylvania Marinho Borralho +7 more
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Epidemiology and genetic diversity of bovine leukemia virus
Virology Journal, 2017 Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses.
Meripet Polat +2 more
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Cytokine secretion in stem cells of cattle infected with bovine leukaemia virus
Journal of Veterinary ResearchBovine leukaemia virus (BLV) is a Deltaretrovirus responsible for enzootic bovine leukosis, the most common neoplastic disease of cattle. It deregulates the immune system, favouring secondary infections and changes in the blood and lymphatic tissues ...
Szczotka Maria, Kuźmak Jacek
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