Recent Advances in BLV Research [PDF]
Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and macaques.
Pierre-Yves Barez +14 more
doaj +2 more sources
Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads [PDF]
Background Bovine Leukemia virus (BLV) is a deltaretrovirus that induces lymphoproliferation and leukemia in ruminants. In ex vivo cultures of B lymphocytes isolated from BLV-infected sheep show that spontaneous apoptosis is reduced.
François Carole +5 more
doaj +2 more sources
Bovine Leukemia Virus DNA in Human Breast Tissue [PDF]
Bovine leukemia virus (BLV), a deltaretrovirus, causes B-cell leukemia/lymphoma in cattle and is prevalent in herds globally. A previous finding of antibodies against BLV in humans led us to examine the possibility of human infection with BLV. We focused
Gertrude Case Buehring +5 more
doaj +2 more sources
Construction and validation of a notification instrument for cases of human T-cell lymphotropic virus infection: methodological study, Natal, 2025 [PDF]
Objectives To construct and validate an instrument for the notification of cases of human T-cell lymphotropic virus infection. Methods This is a methodological study focused on content validation, conducted using the Delphi method in three sequential ...
Renata Olívia Gadelha Romero +6 more
doaj +5 more sources
Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM +6 more
europepmc +2 more sources
Sequencing and phylogenetic analysis of Bovine Leukosis Virus Tax gene in Iran [PDF]
Bovine Leukosis Virus (BLV) belongs to the genus Deltaretrovirus ,subfamily Orthoretrovirinae of the family Retroviridae comprising 3 main genes of gag, pol and env and a number of replication regulatory genes such as Tax, Rex, R III, C IV.
H Momtaz, P Amini, B Abbasian
doaj +1 more source
Milk Macrophage Function in Bovine Leukemia Virus-Infected Dairy Cows
The implications of bovine leukemia virus (BLV) on innate and adaptive immune responses have been widely investigated; however, the effects of BLV on mammary gland immunity require further investigation.
Ewerton de Souza Lima +16 more
doaj +1 more source
Comparison of the Prevalence of Bovine Leukemia Virus (BLV) in Holstein and Angus Cattle Breeds From Shandong Province, China. [PDF]
ABSTRACT Bovine leukemia virus (BLV) is widespread globally and causes economic losses in the cattle industry. Shandong Province plays a significant role in China's livestock industry, with an increasing importance in food of Holstein and Angus cattle. However, BLV prevalence in Holstein and Angus breeds in Shandong Province remains unclear.
Wang J +13 more
europepmc +2 more sources
Computational and Experimental Development of a Novel Multi-Epitope Vaccine Candidate Against Bovine Leukaemia Virus. [PDF]
This study designs a novel multi‐epitope vaccine against bovine leukaemia virus using immunoinformatics. The construct demonstrates high antigenicity, stability, and strong receptor binding, indicating its potential as an effective recombinant vaccine candidate for further experimental validation .
Dini Y +4 more
europepmc +2 more sources
Human T-lymphotropic virus 1 (HTLV-1) is the etiologic agent of adult cell leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Debora Glenda Lima de La-Roque +9 more
doaj +1 more source

