Results 51 to 60 of about 63,443 (281)
Unique Opportunities of Island States to Transition to a Low-Carbon Mobility System [PDF]
, 2020 Small islands developing states (SIDS) contribute minuscule proportions to global greenhouse gas (GHG) emissions and energy consumption, but are highly exposed to climate change impacts, in particular to extreme weather events and sea-level rise. However,
Blechinger, Philipp +2 more
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Improving demand responsive transit services: Insights from the London field test
Journal of Public TransportationThe paper discusses the key insights gained from “GoSutton”, a Demand Responsive Transit (DRT) trial in the borough of Sutton in the suburbs of London during 2019–2020.
Seyedmostafa Zahedi +2 more
doaj +1 more source
Economies in U.S. demand responsive transit
Journal of Advanced Transportation, 1987 AbstractThis paper develops a neoclassical cost function for demand responsive transit (DRT) system and uses it to test the economies of scale hypothesis. The results show economies of scale and further show that the economies can be explained by speed, local and state subsidies, utilization of seating capacity, fleet utilization and an increase in the
openaire +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
An investigation into the feasibility and potential benefits of shared taxi services to commuter stations [PDF]
, 2014 Peer reviewedPublisher ...
Nelson, John D., Wright, Steven
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Smart CitiesA major challenge for modern transit systems relying on traditional fixed-route designs is providing broad accessibility to users. Flex-route transit can enhance accessibility in low-density areas, since it combines the directness of fixed-route transit ...
Joseph Rodriguez +2 more
doaj +1 more source
Performance Measures to Assess Resiliency and Efficiency of Transit Systems [PDF]
, 2017 Transit agencies are interested in assessing the short-, mid-, and long-term performance of infrastructure with the objective of enhancing resiliency and efficiency.
Bartin, Bekir +9 more
core +1 more source