Results 81 to 90 of about 63,551 (239)

An Assessment of Microtransit Impacts on its Substitution and Complementarity with other Modes

Findings
In March of 2022, the Metropolitan Atlanta Rapid Transit Authority, or MARTA, which had previously been a fixed-route system only, implemented a demand-responsive transit system called MARTA Reach.
Maha Ahmad, Lillian Cella, Susan C. Pike, Bailey Affolter, Kari E. Watkins   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Demand-responsive transit systems in areas with low transport demand of “smart city”

Transportation Research Procedia, 2020
Abstract The development of modern telecommunications allows the concept of a “smart city” to increase the flexibility of public transportation significantly and, thus, improve population mobility. In this regard, public transportation represents a demand-responsive transit (DRT) system.
Andrey Gorev, Olga Popova, Aleksandr Solodkij   +2 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

Journal of Transport and Land Use, 2009
Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers.
Anders Wretstrand, Helena Svensson, Sofi Fristedt, Torbjörn Falkmer   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessing Public Transit Network Efficiency and Accessibility in Johor Bahru and Penang, Malaysia: A Data-Driven Approach

Results in Engineering
This study conducts a comprehensive analysis of public bus transit networks in Johor Bahru and Penang, Malaysia, using General Transit Feed Specification (GTFS) data.
Mahbub Hassan, Hridoy Deb Mahin, Ferdoushi Ahmed, Md. Maruf Hassan, Atikur Rahaman, Masuk Abdullah   +5 more
doaj   +1 more source

Arterial traffic signal optimization: a person-based approach [PDF]

, 2013
This paper presents a traffic responsive signal control system that optimizes signal settings based on minimization of person delay on arterials. The system's underlying mixed integer linear program minimizes person delay by explicitly accounting for the
Aboudolas, K., Christofa, E., Skabardonis, A.   +2 more
core  

Towards In-Transit Analytics for Industry 4.0

, 2017
Industry 4.0, or Digital Manufacturing, is a vision of inter-connected services to facilitate innovation in the manufacturing sector. A fundamental requirement of innovation is the ability to be able to visualise manufacturing data, in order to discover ...
Ali, Muhammad, Anjum, Ashiq, Devitt, James, Hill, Richard   +3 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source