Results 1 to 10 of about 1,302,226 (351)
BMC Medical Informatics and Decision Making, 2021 Background Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings.
GBD 2019 Dementia Collaborators
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Biology, 2023 Global cerebral ischemia can elicit rapid innate neuroprotective mechanisms that protect against delayed neuronal death. Brain-derived 17β-estradiol (BDE2), an endogenous neuroprotectant, is synthesized from testosterone by the enzyme aromatase (Aro) and
Jing Xu +7 more
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BMC Geriatrics, 2021 Background Hearing and vision loss in older people has been proven to affect physical and mental health and increase the speed of cognitive decline. Studies have demonstrated that certain practices and improved staff knowledge increase the effective care
Wendy Andrusjak +2 more
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Alzheimer’s Research & Therapy, 2020 Background There is increasing interest in improving understanding of the timing and nature of early neurodegeneration in Alzheimer’s disease (AD) and developing methods to measure this in vivo.
Philip S. J. Weston +12 more
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BMC Public Health, 2023 Background Unmanaged cardiometabolic health, low physical and cognitive activity, poor diet, obesity, smoking and excessive alcohol consumption are modifiable health risk factors for dementia and public health approaches to dementia prevention have been ...
Larissa Bartlett +9 more
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BMC Health Services Research, 2021 Background Dementia Care Mapping™ (DCM) is a widely used, staff-led, psychosocial intervention to support the implementation of person-centred care. Efficacy evaluations in care homes have produced mixed outcomes, with implementation problems identified.
Alys Wyn Griffiths +4 more
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What Can Quantitative Gait Analysis Tell Us about Dementia and Its Subtypes? A Structured Review [PDF]
, 2017 Distinguishing dementia subtypes can be difficult due to similarities in clinical presentation. There is increasing interest in discrete gait characteristics as markers to aid diagnostic algorithms in dementia.
Galna, Brook +5 more
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Bilingualism Is Associated with a Delayed Onset of Dementia but Not with a Lower Risk of Developing it: a Systematic Review with Meta-Analyses. [PDF]
, 2020 Some studies have linked bilingualism with a later onset of dementia, Alzheimer's disease (AD), and mild cognitive impairment (MCI). Not all studies have observed such relationships, however.
Brini, S. +9 more
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Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
EMBO Molecular Medicine, 2021 On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (
Giovanna Lalli +3 more
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Dementia Prevalence Estimates in Sub-Saharan Africa: Comparison of two Diagnostic Criteria. [PDF]
, 2013 We have previously reported the prevalence of dementia in older adults living in the rural Hai district of Tanzania according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria.
Chaote, Paul +9 more
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