Results 11 to 20 of about 736,538 (311)

Care home design for people with dementia: What do people with dementia and their family carers value? [PDF]

, 2011
Objectives: To report on the views of people with dementia who live in care homes and their family carers on aspects of design that are important to them, and discuss these in relation to developing physical care environments that respond to the wishes ...
Innes, Anthea, Dincarslan, Ozlem, Fiona Kelly, Ozlem Dincarslan, Kelly, Fiona, Anthea Innes, Dincarslan, O.   +6 more
core   +1 more source

Abusive Interactions: Research in Locked Wards for People with dementia [PDF]

, 2010
This paper reports on a study in which unique access to 3 locked psycho-geriatric wards of a hospital allowed ethnographic exploration into everyday social worlds of fourteen people with dementia.
Kelly, Fiona
core   +1 more source

A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study

Alzheimer’s Research & Therapy, 2018
Background The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.
Basil H. Ridha, Sebastian Crutch, Dawn Cutler, Christopher Frost, William Knight, Suzie Barker, Norah Epie, Elizabeth K. Warrington, Riitta Kukkastenvehmas, Jane Douglas, Martin N. Rossor   +10 more
doaj   +1 more source

Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?

EMBO Molecular Medicine, 2021
On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (
Giovanna Lalli, Jonathan M Schott, John Hardy, Bart De Strooper   +3 more
doaj   +1 more source

Supporting User Participation in Local Policy Development: The Fife Dementia Strategy [PDF]

, 2012
This article reviews the consultation process during the development of a local dementia strategy. The processes of involvement by the range of stakeholders involved and how their different views shaped the strategy are considered.
Bradley, Brittany Ellis, McCabe, Louise, Ellis Bradley, Brittany   +2 more
core   +1 more source

Investigation of early molecular alterations in tauopathy with generative adversarial networks

Scientific Reports, 2023
The recent advances in deep learning-based approaches hold great promise for unravelling biological mechanisms, discovering biomarkers, and predicting gene function.
Hyerin Kim, Yongjin Kim, Chung-Yeol Lee, Do-Geun Kim, Mookyung Cheon   +4 more
doaj   +1 more source

The impact of location on satisfaction with dementia services amongst people with dementia and their informal carers: a comparative evaluation of a community-based and a clinic-based memory service [PDF]

, 2007
Background: The development of effective medication for the treatment of Alzheimer's disease led to an expansion in the use of memory clinics ther clinic-based services for the delivery and monitoring of the drugs.
Gibson, Grant, Wattis, John, Timlin, Alison, Curran, Stephen   +3 more
core   +1 more source

Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression

npj Parkinson's Disease, 2022
Depression is a common non-motor feature of Parkinson’s disease (PD) which confers significant morbidity and is challenging to treat. The thalamus is a key component in the basal ganglia-thalamocortical network critical to the pathogenesis of PD and ...
R. Bhome, A. Zarkali, G. E. C. Thomas, J. E. Iglesias, J. H. Cole, R. S. Weil   +5 more
doaj   +1 more source

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience [PDF]

, 2008
Background: Dementia results from heterogeneous diseases of the brain. Mixed disease forms are increasingly recognized. Methods: We performed a survey within brain banks of BrainNet Europe to estimate the proportion of mixed disease forms underlying ...
Gelpi, Ellen, Kretzschmar H, Alafuzoff, Irina, Alafuzoff I, Budka H., Nagy, Zoltan, Seilhean, Danielle, Ferrer I, Arzberger, Thomas, Al-Sarraj, Safa, Gelpi E, Kovacs, Gabor G., Kretzschmar, Hans, Soininen, Hilkka, Troakes, Claire, Nagy Z, Capellari, Sabina, Seilhean D, Kövari V, Budka, Herbert, Al Sarraj S, Troakes C, Alafuzoff, Irina,, Arzberger T, Ferrer, Isidro, Bogdanovic, Nenad, Bogdanovic N, Kovari, Viktor, Soininen H, Parchi, Piero, Kovacs GG, Ferrer, I, Alafuzoff, I, Capellari, S, Kovacs, GG, Gelpi, E, Al-Sarraj, S, Bogdanovic, N,, Kovari, V, Arzberger, T, Kretzschmar, H   +40 more
core   +1 more source

Factors associated with successful dementia education for practitioners in primary care: an in-depth case study

BMC Medical Education, 2019
Background With increasing numbers of people in the UK living with dementia, the provision of good quality person-centred care that meets the often complex needs of this population is required.
Cara Sass, Natasha Burnley, Michelle Drury, Jan Oyebode, Claire Surr   +4 more
doaj   +1 more source