Alzheimer’s Research & Therapy, 2018 Background The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.
Basil H. Ridha +10 more
doaj +1 more source
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
EMBO Molecular Medicine, 2021 On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (
Giovanna Lalli +3 more
doaj +1 more source
Undiagnosed dementia in primary care: A record linkage study [PDF]
, 2020 BackgroundThe number of people living with dementia is greater than the number with a diagnosis of dementia recorded in primary care. This suggests that a significant number are living with dementia that is undiagnosed.
Aldus, Clare +11 more
core +2 more sources
Investigation of early molecular alterations in tauopathy with generative adversarial networks
Scientific Reports, 2023 The recent advances in deep learning-based approaches hold great promise for unravelling biological mechanisms, discovering biomarkers, and predicting gene function.
Hyerin Kim +4 more
doaj +1 more source
A systematic literature review on nurses' and health care support workers' experiences of caring for people with dementia on orthopaedic wards [PDF]
, 2016 Aims and objectives To review literature on nurses’ and health care workers’ experiences of caring for people with dementia on orthopaedic wards. Background Dementia is a condition that affects a large number of the older population worldwide.
Likupe, Gloria, Moonga, Jubilee
core +1 more source
Bilingualism Is Associated with a Delayed Onset of Dementia but Not with a Lower Risk of Developing it: a Systematic Review with Meta-Analyses. [PDF]
, 2020 Some studies have linked bilingualism with a later onset of dementia, Alzheimer's disease (AD), and mild cognitive impairment (MCI). Not all studies have observed such relationships, however.
Brini, S. +9 more
core +3 more sources
Supporting general hospital staff to provide dementia sensitive care: A realist evaluation [PDF]
, 2019 © 2019 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0).Background: There are an increasing number of interventions to improve hospital care for ...
Bunn, Frances +2 more
core +2 more sources
Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression
npj Parkinson's Disease, 2022 Depression is a common non-motor feature of Parkinson’s disease (PD) which confers significant morbidity and is challenging to treat. The thalamus is a key component in the basal ganglia-thalamocortical network critical to the pathogenesis of PD and ...
R. Bhome +5 more
doaj +1 more source
‘Our voice started off as a whisper and now it is a great big roar’ : The Salford Dementia Associate Panel as a model of involvement in research activities [PDF]
, 2020 This paper presents the work of the ‘Salford Dementia Associate Panel’, based at the Salford Institute for Dementia, Salford University (UK). We discuss the roles of the Dementia Associates, in particular around the areas of engagement and research.
Allcroft, F +9 more
core +3 more sources
Finding a way: long-term care homes to support dementia [PDF]
, 2015 An ageing demographic has increased the number of people with dementia. Although dementia is commonly associated with memory loss, other early symptoms include difficulty with wayfinding.
Alzheimer's Society +20 more
core +1 more source