Results 151 to 160 of about 262,612 (300)

Associations between body mass index categories and geriatric assessment tests among older adults with chronic kidney disease: A prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background The optimal body mass index (BMI) among older adults with chronic kidney disease (CKD) in geriatric assessment tests has not been studied. This study investigates the relationship between BMI and Comprehensive Geriatric Assessment (CGA) parameters among older adults with CKD.
Yelda Deligöz Bildaci, Cihan Heybeli, Lee Smith, Masoud Rahmati, Dong Keon Yon, Pinar Soysal   +5 more
wiley   +1 more source

Wasting syndrome as a predictive factor for adverse health outcomes in older adults: A prospective cohort study

Nutrition in Clinical Practice, EarlyView.
Abstract Wasting syndrome (WS), also known as unintentional weight loss, is defined as a 5% reduction in body weight over a period of 6–12 months. The mortality associated with WS in older adults has not been adequately explored. The objective of this study was to investigate this relationship in hospitalized older individuals over an 18‐month period ...
Roana Carolina Bezerra dos Santos, Cláudia Porto Sabino Pinho, Eduila Maria Couto Santos, Maria Caroline da Silva Patricio, Stefany Beatriz do Nascimento, Letícia Sabino Santos, Taynara de Sousa Rego Mendes, Alcides da Silva Diniz   +7 more
wiley   +1 more source

Is the incidence of dementia declining? [PDF]

Action on preventative health could lower the risk of dementia for future generations, argues this report. Executive summary The world-wide projections of the prevalence of dementia in the coming decades have been a source of great concern to health ...
Perminder S. Sachdev
core  

Pilot study on the use of a multimorbidity index in patients receiving home parenteral nutrition

Nutrition in Clinical Practice, EarlyView.
Abstract Background Home parenteral nutrition (HPN) patients often have multiple comorbidities. A validated multimorbidity index (MMI) could help determine resource needs and risks with HPN. We evaluated MMI scoring to determine if it predicted HPN resource use and outcomes.
Michael M. Rothkopf, Mohan Pant, Zachary Rothkopf, Rebecca Brown, Jamie Haselhorst, Debbie L. Stevenson, Andrew DePalma, Michael Saracco   +7 more
wiley   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

Obesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden, Maria A. Oquendo, Robert F. Kushner, Dachuang Cao, Chrisanthi A. Karanikas, Afton Kechter, Madhumita A. Murphy   +6 more
wiley   +1 more source

Facial Nerve Palsy in Malignant Otitis Externa Hospitalizations: Outcomes and Risk Factors

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To provide a description of the occurrence of facial nerve palsy in hospitalizations for malignant otitis externa and to compare the demographic characteristics, hospital traits, comorbidities, and outcomes between patients with and without palsy. Study Design Retrospective cross‐sectional database study.
Emma R. Thompson, Anthony M. Saad, Sean Z. Haimowitz, Nour H. Abdel‐Azim, Kevin Wong, Andrey Filimonov   +5 more
wiley   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Associations of Vestibular Disorders With Risk of All‐Cause and Cause‐Specific Dementia: A Longitudinal Cohort Study in UK Biobank

Sensory Neuroscience, EarlyView.
ABSTRACT To explore associations of vestibular disorders with all‐cause and cause‐specific dementia and underlying biological mechanisms/neuroimaging changes. A population‐based cohort study of 406,348 UK Biobank participants was conducted. Inverse probability of treatment weighting (IPTW) balanced baseline covariates, and Cox proportional hazards ...
Xiaofei Li, Fan Jiang, Qiuyue Dong, Hao Chen, Hanbing Ji, Alimu Dayimu, Yifan Yu, Guorong Li, Na Li, Peipei Fu, Qi Jing, Maoli Duan, Hongkai Li, Shanquan Chen, Daogong Zhang, Haibo Wang   +15 more
wiley   +1 more source

Hearing loss in the young-old is associated with increased risk for Alzheimer's disease and vascular dementia. [PDF]

J Alzheimers Dis
Francis L, Beiser A, Lu S, Kujawa SG, Heard-Costa N, Kolo FB, Kamboh MI, Bernal R, Welling DB, Alcabes RL, Himali JJ, Seshadri S.   +11 more
europepmc   +1 more source