Results 151 to 160 of about 1,302,226 (351)

Ueber die acut verlaufenden Erkrankungen an Dementia paralytica [PDF]

, 1902
Buchholz
openalex   +1 more source

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

Advanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo, Youngjun Kim, Rian Kang, Seho Lee, Dang Du Nguyen, Soomin Park, Dongjoon Lee, Jong Won Han, Inhee Mook‐Jung, Luke P. Lee, Jong‐Chan Park, Inki Kim   +11 more
wiley   +1 more source

People Living With Dementia and Their Families as Educators for Social Justice

Health Expectations
Background It is increasingly recognised that dementia education and training should include the direct voices of Experts by Experience (people living with dementia and their families).
Clare Mason, Ana Barbosa, Danielle Jones, Michael Andrews, Andrea Capstick   +4 more
doaj   +1 more source

Ueber den Zustand des Rückenmarkes in der Dementia paralytica und die Verbreitung der Körnebenzellen-Myelitis [PDF]

, 1870
Th. Simon
openalex   +1 more source

Dementia prevention, intervention, and care

The Lancet, 2017
G. Livingston, A. Sommerlad, V. Orgeta, S. Costafreda, Jonathan Huntley, D. Ames, C. Ballard, Sube Banerjee, A. Burns, J. Cohen-Mansfield, C. Cooper, Nick Fox, L. Gitlin, R. Howard, H. Kales, E. Larson, K. Ritchie, K. Rockwood, E. Sampson, Quincy M. Samus, L. Schneider, G. Selbæk, L. Teri, N. Mukadam   +23 more
semanticscholar   +1 more source

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy

Cell Reports
Summary: Dysfunction of the blood-brain barrier (BBB) is recognized as a key factor in the progression of neurodegenerative diseases (NDs), but the detailed mechanisms behind its pathogenesis and impact on neurodegeneration remain elusive.
Min-Tae Jeon, Sinnead Anne Cogill, Kyu-Sung Kim, Yongjin Kim, Hyerin Kim, Chung-Yeol Lee, Suji Kim, Suhyeon Son, Jeongyeon Kim, Jaehyeok Lee, Inyeong Park, Mookyung Cheon, Do-Geun Kim   +12 more
doaj   +1 more source

LISSAUER'S DEMENTIA PARALYTICA: CONTRIBUTION TO THE STUDY OF ITS DIAGNOSIS AND PATHOGENESIS [PDF]

, 1942
Andrew Galbraith, Aaron M. Meyer
openalex   +1 more source

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

Advanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin, Chang Che, Aimin Jiang, Chang Qi, Antonino Glaviano, Zhijie Zhao, Zhirou Zhang, Zaoqu Liu, Ziyao Zhou, Quan Cheng, Shuofeng Yuan, Peng Luo   +11 more
wiley   +1 more source

An Automated Micro‐Immunobeads‐Based Electromagnetic Operation System (MEMOs) for Blood Testing of Alzheimer's Disease

Advanced Science, EarlyView.
This work presents an automated and accessible point‐of‐care device, MEMOs, for the detection of exosomal Aβ42 protein, a potential blood biomarker for Alzheimer’s disease. MEMOs, with its automated operation workflow, minimizes hands‐on time and maintains high sensitivity in diagnosing AD, allowing non‐specialists to conduct tests at home and offering
Xiaoxue Fan, Xinyu Ye, Jiangrui Xu, Tianjiao Mao, Ruotong Zhang, Xinyuan Zhou, Christina C. K. Au Yeung, Chang Li, Raymond Chuen‐Chung Chang, Haisong Lin, Ho Cheung Shum   +10 more
wiley   +1 more source