Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study [PDF]
, 2022 Honghuang Lin +10 more
openalex +1 more source
Advanced Science, EarlyView.Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz +5 more
wiley +1 more source
Dementia prevention, intervention, and care
The Lancet, 2017 G. Livingston +23 more
semanticscholar +1 more source
Transcriptional targets of amyotrophic lateral sclerosis/frontotemporal dementia protein TDP-43 – meta-analysis and interactive graphical database [PDF]
, 2022 Maize C. Cao, Emma L. Scotter
openalex +1 more source
Advanced Science, EarlyView.A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai +12 more
wiley +1 more source
The relationship of dementia prevalence in older adults with intellectual disability (ID) to age and severity of ID [PDF]
, 2009 Background: Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We
Hassiotis, A. +3 more
core
Patterns of staging, treatment, and mortality in gastric, colorectal, and lung cancer among older adults with and without preexisting dementia: a Japanese multicentre cohort study [PDF]
, 2023 Toshitaka Morishima +7 more
openalex +1 more source
Advanced Science, EarlyView.Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie +18 more
wiley +1 more source
People Living With Dementia and Their Families as Educators for Social Justice
Health ExpectationsBackground It is increasingly recognised that dementia education and training should include the direct voices of Experts by Experience (people living with dementia and their families).
Clare Mason +4 more
doaj +1 more source
Longitudinal evolution of cortical thickness signature reflecting Lewy body dementia in isolated REM sleep behavior disorder: a prospective cohort study [PDF]
, 2023 Jung Hwan Shin +6 more
openalex +1 more source