Results 171 to 180 of about 1,330,157 (395)

Prevalence of disability according to multimorbidity and disease clustering: a population-based study [PDF]

open access: yes, 2011
Background: The prevalence of chronic diseases has increased with population ageing, and research has attempted to elucidate the correlation between chronic diseases and disability. However, most studies in older populations have focused on the effect of
Angleman, Sara   +2 more
core   +1 more source

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

open access: yesAdvanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang   +7 more
wiley   +1 more source

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

open access: yesAdvanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li   +8 more
wiley   +1 more source

Neuronal Circuit Dysfunction in Amyotrophic Lateral Sclerosis

open access: yesCells
The primary neural circuit affected in Amyotrophic Lateral Sclerosis (ALS) patients is the corticospinal motor circuit, originating in upper motor neurons (UMNs) in the cerebral motor cortex which descend to synapse with the lower motor neurons (LMNs) in
Andrea Salzinger   +4 more
doaj   +1 more source

Satisfaction with Care among Residents and Families in a Long-Term and Complex Continuing Care Organization [PDF]

open access: yes, 2008
This article looks at one organization’s implementation of a satisfaction survey for all of its residents. It also explores how satisfaction ratings vary between complex continuing care (CCC) and long-term care (LTC) residents between residents with and ...
Brazil, Kevin   +6 more
core   +1 more source

An Automated Micro‐Immunobeads‐Based Electromagnetic Operation System (MEMOs) for Blood Testing of Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This work presents an automated and accessible point‐of‐care device, MEMOs, for the detection of exosomal Aβ42 protein, a potential blood biomarker for Alzheimer’s disease. MEMOs, with its automated operation workflow, minimizes hands‐on time and maintains high sensitivity in diagnosing AD, allowing non‐specialists to conduct tests at home and offering
Xiaoxue Fan   +10 more
wiley   +1 more source

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.

open access: yesBrain : a journal of neurology, 2011
K. Rascovsky   +45 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy