Results 11 to 20 of about 579,799 (311)
'The dementia case-finding tool can be used by care workers to identify care home residents who may have dementia. Used before a clinician's visit, it means their time is more focused'.
Ljubenkov, Peter A, Geschwind, Michael D
+9 more sources
Background Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic evaluations of dementia prevalence are prohibitively resource-intensive in many settings.
GBD 2019 Dementia Collaborators
doaj +1 more source
Global cerebral ischemia can elicit rapid innate neuroprotective mechanisms that protect against delayed neuronal death. Brain-derived 17β-estradiol (BDE2), an endogenous neuroprotectant, is synthesized from testosterone by the enzyme aromatase (Aro) and
Jing Xu +7 more
doaj +1 more source
Background Hearing and vision loss in older people has been proven to affect physical and mental health and increase the speed of cognitive decline. Studies have demonstrated that certain practices and improved staff knowledge increase the effective care
Wendy Andrusjak +2 more
doaj +1 more source
Background There is increasing interest in improving understanding of the timing and nature of early neurodegeneration in Alzheimer’s disease (AD) and developing methods to measure this in vivo.
Philip S. J. Weston +12 more
doaj +1 more source
Background Unmanaged cardiometabolic health, low physical and cognitive activity, poor diet, obesity, smoking and excessive alcohol consumption are modifiable health risk factors for dementia and public health approaches to dementia prevention have been ...
Larissa Bartlett +9 more
doaj +1 more source
Background Dementia Care Mapping™ (DCM) is a widely used, staff-led, psychosocial intervention to support the implementation of person-centred care. Efficacy evaluations in care homes have produced mixed outcomes, with implementation problems identified.
Alys Wyn Griffiths +4 more
doaj +1 more source
Background The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.
Basil H. Ridha +10 more
doaj +1 more source
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (
Giovanna Lalli +3 more
doaj +1 more source
Investigation of early molecular alterations in tauopathy with generative adversarial networks
The recent advances in deep learning-based approaches hold great promise for unravelling biological mechanisms, discovering biomarkers, and predicting gene function.
Hyerin Kim +4 more
doaj +1 more source

