Results 11 to 20 of about 1,350,087 (353)

The worldwide costs of dementia in 2019

open access: yesAlzheimer's & Dementia, 2023
Dementia is a leading cause of death and disability globally. Estimating total societal costs demonstrates the wide impact of dementia and its main direct and indirect economic components.
A. Wimo   +13 more
semanticscholar   +1 more source

The inter-relationship between delirium and dementia: the importance of delirium prevention

open access: yesNature Reviews Neurology, 2022
Delirium and dementia are two frequent causes of cognitive impairment among older adults and have a distinct, complex and interconnected relationship.
T. Fong, S. Inouye
semanticscholar   +1 more source

Physical activity as a protective factor for dementia and Alzheimer’s disease: systematic review, meta-analysis and quality assessment of cohort and case–control studies

open access: yesBritish Journal of Sports Medicine, 2022
Objective Physical activity (PA) is associated with a decreased incidence of dementia, but much of the evidence comes from short follow-ups prone to reverse causation. This meta-analysis investigates the effect of study length on the association.
Paula Iso-Markku   +5 more
semanticscholar   +1 more source

Association of sleep duration in middle and old age with incidence of dementia

open access: yesNature Communications, 2021
Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration prior to old age is associated with dementia incidence. Using data from 7959 participants of the Whitehall II study, we examined the association between sleep ...
S. Sabia   +8 more
semanticscholar   +1 more source

Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI).

open access: yesCochrane Database of Systematic Reviews, 2021
BACKGROUND Dementia is a progressive global cognitive impairment syndrome. In 2010, more than 35 million people worldwide were estimated to be living with dementia.
I. Arévalo-Rodriguez   +8 more
semanticscholar   +1 more source

A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study

open access: yesAlzheimer’s Research & Therapy, 2018
Background The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.
Basil H. Ridha   +10 more
doaj   +1 more source

Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?

open access: yesEMBO Molecular Medicine, 2021
On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (
Giovanna Lalli   +3 more
doaj   +1 more source

Dementia, music and biometric gaming: Rising to the Dementia Challenge [PDF]

open access: yes, 2015
In 2012, the U.K. government launched its Dementia Challenge, authorizing additional funding for dementia research and health care. The search for curative medicines is ongoing, but scientific research reveals evidence that music can play a positive role
Guétin S., Helen R. Mitchell, Kubota N.
core   +1 more source

Investigation of early molecular alterations in tauopathy with generative adversarial networks

open access: yesScientific Reports, 2023
The recent advances in deep learning-based approaches hold great promise for unravelling biological mechanisms, discovering biomarkers, and predicting gene function.
Hyerin Kim   +4 more
doaj   +1 more source

Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]

open access: yes, 2017
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
core   +1 more source

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