Results 11 to 20 of about 50 (42)
Dementia often is defined as a progressive cognitive disturbance leading to a loss of independent function. Most clinicians are familiar with the typical pattern of amnestic Alzheimer's disease, the most common neurodegenerative presentation of dementia.
Ljubenkov, Peter A, Geschwind, Michael D
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AbstractThe ageing revolution is changing the composition of our society with more people becoming very old with higher risks for developing both pain and dementia. Pain is normally signaled by verbal communication, which becomes more and more deteriorated in people with dementia.
Achterberg, Wilco+4 more
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Vascular dementia is one of the most frequently occurring dementia syndromes. Its prevalence is about 5% among subjects above 85 years of age. Elevated blood pressure and atherosclerosis are the most important risk factors. According to international criteria, vascular dementia usually occurs within three months after having a stroke.
Leeuw, H.F. de, Gijn, J. van
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Dementia is a progressive decline in the ability to remember, learn, understand, and communicate. Alzheimer's disease (AD) represents the most common form of dementia in the elderly, affecting about 28 million individuals worldwide. Current treatments for AD and other dementias are sorely limited, falling short of preventing or significantly slowing ...
COPPEDE', FABIO+3 more
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(Reprinted with permission from Lancet 2015; 386:1698-706).
O'Brien JT, Thomas A
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Senile Dementia and Presenile Dementia
Neurotransmitters including acetylcholine, dopamine, norepinephrine, serotonin, GABA and vasopressin were examined in control subjects and patients with Alzheimer-type dementia, involving presenile and senile dementia. Neurotransmitters exhibited various mode of changes with aging.
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Memantine is a moderate affinity uncompetitive antagonist of glutamate NMDA receptors. It is licensed for use in moderate and severe Alzheimer's disease (AD); in the USA, it is also widely used off-label for mild AD.To determine efficacy and safety of memantine for people with dementia. To assess whether memantine adds benefit for people already taking
Jennifer Ware+8 more
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AbstractObjectiveDementia is prevalent in older adults and the population is ageing. Many factors have been associated with dementia and anything that may aid the prevention of dementia is of importance.MethodThe literature in this area was evaluated and information relating to the various factors that may impact upon the prevention of dementia is ...
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Dementia is a clinical diagnosis requiring new functional dependence on the basis of progressive cognitive decline. It is estimated that 1.3% of the entire UK population, or 7.1% of those aged 65 or over, have dementia. Applying these to 2013 population estimates gives an estimated number of 19,765 people living with dementia in Northern Ireland.
Cunningham, E L+3 more
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