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Dementia often is defined as a progressive cognitive disturbance leading to a loss of independent function. Most clinicians are familiar with the typical pattern of amnestic Alzheimer's disease, the most common neurodegenerative presentation of dementia.
Ljubenkov, Peter A, Geschwind, Michael D
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AbstractThe ageing revolution is changing the composition of our society with more people becoming very old with higher risks for developing both pain and dementia. Pain is normally signaled by verbal communication, which becomes more and more deteriorated in people with dementia.
Achterberg, Wilco+4 more
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Vascular dementia is one of the most frequently occurring dementia syndromes. Its prevalence is about 5% among subjects above 85 years of age. Elevated blood pressure and atherosclerosis are the most important risk factors. According to international criteria, vascular dementia usually occurs within three months after having a stroke.
Leeuw, H.F. de, Gijn, J. van
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Background The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.
Basil H. Ridha+10 more
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Background With increasing numbers of people in the UK living with dementia, the provision of good quality person-centred care that meets the often complex needs of this population is required.
Cara Sass+4 more
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Background The Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied on self-report or proxies for dementia such as cognitive tests. Our aims were twofold: a) to describe a
Donncha S. Mullin+15 more
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Introduction Containment measures implemented to minimize the spread of coronavirus disease 2019 (COVID‐19) are reported to be negatively affecting mental health, diet, and alcohol consumption.
Larissa Bartlett+7 more
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Physiological phenotyping of dementias using emotional sounds
Introduction Emotional behavioral disturbances are hallmarks of many dementias but their pathophysiology is poorly understood. Here we addressed this issue using the paradigm of emotionally salient sounds.
Phillip D. Fletcher+10 more
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Dementias show differential physiological responses to salient sounds
Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals,
Phillip David Fletcher+10 more
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Dementia is a progressive decline in the ability to remember, learn, understand, and communicate. Alzheimer's disease (AD) represents the most common form of dementia in the elderly, affecting about 28 million individuals worldwide. Current treatments for AD and other dementias are sorely limited, falling short of preventing or significantly slowing ...
COPPEDE', FABIO+3 more
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