Experiences of end of life amongst family carers of people with advanced dementia: longitudinal cohort study with mixed methods [PDF]
, 2017 Kirsten Moore +10 more
openalex +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science, EarlyView.This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source
Satisfaction with Care among Residents and Families in a Long-Term and Complex Continuing Care Organization [PDF]
, 2008 This article looks at one organization’s implementation of a satisfaction survey for all of its residents. It also explores how satisfaction ratings vary between complex continuing care (CCC) and long-term care (LTC) residents between residents with and ...
Brazil, Kevin +6 more
core +1 more source
Advanced Science, EarlyView.The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang +22 more
wiley +1 more source
Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia
, 2018 Tavia E. Evans +8 more
openalex +1 more source
Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study [PDF]
, 2019 Anette Hall +14 more
openalex +1 more source
Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice
Advanced Science, EarlyView.Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao +12 more
wiley +1 more source
Older Primary Care Patients’ Attitudes and Willingness to Screen for Dementia [PDF]
, 2015 Nicole R. Fowler +6 more
openalex +1 more source
Advanced Science, EarlyView.Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang +13 more
wiley +1 more source
Effects of Exergaming in People with Dementia: Results of a Systematic Literature Review
, 2018 Joeke van Santen +7 more
openalex +2 more sources