Results 21 to 30 of about 940,684 (303)

A critical literature review exploring the challenges of delivering effective palliative care to older people with dementia in the acute hospital setting [PDF]

open access: yes, 2008
Aim. This paper considers the challenges of delivering effective palliative care to older people with dementia and the possible strategies to overcome barriers to endof-life care in these patients. Background.
Birch, Deborah, Draper, Janet
core   +1 more source

Factors associated with successful dementia education for practitioners in primary care: an in-depth case study

open access: yesBMC Medical Education, 2019
Background With increasing numbers of people in the UK living with dementia, the provision of good quality person-centred care that meets the often complex needs of this population is required.
Cara Sass   +4 more
doaj   +1 more source

A systematic review and meta-analysis on the prevalence of dementia in europe. estimates from the highest-quality studies adopting the dsm iv diagnostic criteria [PDF]

open access: yes, 2018
BACKGROUND: Dementia, including Alzheimer's disease (AD), is one of the most burdensome medical conditions. Usually, the reviews that aim at calculating the prevalence of dementia include estimates from studies without assessing their methodological ...
Bacigalupo, I   +7 more
core   +1 more source

Physiological phenotyping of dementias using emotional sounds

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2015
Introduction Emotional behavioral disturbances are hallmarks of many dementias but their pathophysiology is poorly understood. Here we addressed this issue using the paradigm of emotionally salient sounds.
Phillip D. Fletcher   +10 more
doaj   +1 more source

Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]

open access: yes, 2017
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
core   +1 more source

Drawn from life: Cocreating narrative and graphic vignettes of lived experience with people affected by dementia

open access: yesHealth Expectations, 2021
Background The growing literature on Patient and Public Involvement and Engagement (PPIE) and dementia identifies specific problems related to the influence that involvement has on research outcomes, over‐reliance on family members as proxies and lack of
Andrea Capstick   +7 more
doaj   +1 more source

Activation of NMDA receptors in brain endothelial cells increases transcellular permeability

open access: yesFluids and Barriers of the CNS, 2022
Neurovascular coupling is a precise mechanism that induces increased blood flow to activated brain regions, thereby providing oxygen and glucose.
Kyu-Sung Kim   +4 more
doaj   +1 more source

Through the eyes of others - The social experiences of people with dementia: A systematic literature review and synthesis [PDF]

open access: yes, 2017
Psychosocial models suggest that the lived experience of dementia is affected by interpersonal factors such as the ways in which others view, talk about, and behave toward the person with dementia.
Clarke, Chris   +7 more
core   +1 more source

The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

open access: yesExperimental and Molecular Medicine, 2020
Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to determine how an aggregate-forming protein common to several neurodegenerative disorders propagates throughout the brain.
Myungjin Jo   +5 more
doaj   +1 more source

Identifying dementia using medical data linkage in a longitudinal cohort study: Lothian Birth Cohort 1936

open access: yesBMC Psychiatry, 2023
Background The Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied on self-report or proxies for dementia such as cognitive tests. Our aims were twofold: a) to describe a
Donncha S. Mullin   +15 more
doaj   +1 more source

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