Results 31 to 40 of about 1,330,157 (395)

Through the eyes of others - The social experiences of people with dementia: A systematic literature review and synthesis [PDF]

, 2017
Psychosocial models suggest that the lived experience of dementia is affected by interpersonal factors such as the ways in which others view, talk about, and behave toward the person with dementia.
Clarke, Chris, Clarke, Christopher, Moniz-Cook, Esme, Moniz-Cook, Esme D., Patterson, Kirsty, Patterson, Kirsty M., Wolverson, Emma, Wolverson, Emma L.   +7 more
core   +1 more source

Physiological phenotyping of dementias using emotional sounds

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2015
Introduction Emotional behavioral disturbances are hallmarks of many dementias but their pathophysiology is poorly understood. Here we addressed this issue using the paradigm of emotionally salient sounds.
Phillip D. Fletcher, Jennifer M. Nicholas, Timothy J. Shakespeare, Laura E. Downey, Hannah L. Golden, Jennifer L. Agustus, Camilla N. Clark, Catherine J. Mummery, Jonathan M. Schott, Sebastian J. Crutch, Jason D. Warren   +10 more
doaj   +1 more source

Identifying dementia using medical data linkage in a longitudinal cohort study: Lothian Birth Cohort 1936

BMC Psychiatry, 2023
Background The Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied on self-report or proxies for dementia such as cognitive tests. Our aims were twofold: a) to describe a
Donncha S. Mullin, Lucy E. Stirland, Emily Buchanan, Catherine-Anne Convery, Simon R. Cox, Ian J. Deary, Cinzia Giuntoli, Holly Greer, Danielle Page, Elizabeth Robertson, Susan D. Shenkin, Anna Szalek, Adele Taylor, Georgina Weatherdon, Tim Wilkinson, Tom C. Russ   +15 more
doaj   +1 more source

A critical literature review exploring the challenges of delivering effective palliative care to older people with dementia in the acute hospital setting [PDF]

, 2008
Aim. This paper considers the challenges of delivering effective palliative care to older people with dementia and the possible strategies to overcome barriers to endof-life care in these patients. Background.
Birch, Deborah, Draper, Janet
core   +1 more source

The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

Experimental and Molecular Medicine, 2020
Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to determine how an aggregate-forming protein common to several neurodegenerative disorders propagates throughout the brain.
Myungjin Jo, Shinrye Lee, Yu-Mi Jeon, Seyeon Kim, Younghwi Kwon, Hyung-Jun Kim   +5 more
doaj   +1 more source

Activation of NMDA receptors in brain endothelial cells increases transcellular permeability

Fluids and Barriers of the CNS, 2022
Neurovascular coupling is a precise mechanism that induces increased blood flow to activated brain regions, thereby providing oxygen and glucose.
Kyu-Sung Kim, Min Tae Jeon, Eun Seon Kim, Chan Hee Lee, Do-Geun Kim   +4 more
doaj   +1 more source

A systematic review and meta-analysis on the prevalence of dementia in europe. estimates from the highest-quality studies adopting the dsm iv diagnostic criteria [PDF]

, 2018
BACKGROUND: Dementia, including Alzheimer's disease (AD), is one of the most burdensome medical conditions. Usually, the reviews that aim at calculating the prevalence of dementia include estimates from studies without assessing their methodological ...
Bacigalupo, I, Canevelli, M, Di Fiandra, T, Di Pucchio, A, Lacorte, E, Marzolini, F, Mayer, F, Vanacore, N.   +7 more
core   +1 more source

Dementias show differential physiological responses to salient sounds

Frontiers in Behavioral Neuroscience, 2015
Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals,
Phillip David Fletcher, Jennifer eNicholas, Timothy J Shakespeare, Laura eDowney, Hannah eGolden, Jennifer L Agustus, Camilla eClark, Cath eMummery, Jonathan eSchott, Sebastian eCrutch, Jason eWarren   +10 more
doaj   +1 more source

Socioeconomic status as a risk factor for dementia death:individual participant meta-analysis of 86 508 men and women from the UK [PDF]

, 2013
Background Life-course socioeconomic factors may have a role in dementia aetiology but there is a current paucity of studies. Meta-analyses of individual participant data would considerably strengthen this evidence base.
Cox, Emmanuel Stamatakis, Ferri, G. David Batty, John M. Starr, Mark Hamer, Marmot, Mika Kivimäki, MRC, Norton, Snowdon, Tom C. Russ, von Elm   +12 more
core   +1 more source

Diagnosis and management of dementia with Lewy bodies

Neurology, 2017
The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade.
I. McKeith, B. Boeve, D. Dickson, G. Halliday, John-Paul Taylor, D. Weintraub, D. Aarsland, J. Galvin, J. Attems, C. Ballard, Ashley Bayston, T. Beach, F. Blanc, N. Bohnen, L. Bonanni, J. Bras, P. Brundin, D. Burn, A. Chen-Plotkin, J. Duda, O. El‐Agnaf, H. Feldman, T. Ferman, D. Ffytche, H. Fujishiro, D. Galasko, J. Goldman, S. Gomperts, N. Graff-Radford, L. Honig, Á. Iranzo, K. Kantarci, D. Kaufer, W. Kukull, V. Lee, J. Leverenz, S. Lewis, C. Lippa, A. Lunde, M. Masellis, E. Masliah, P. McLean, B. Mollenhauer, T. Montine, E. Moreno, E. Mori, Melissa M Murray, J. O'Brien, Sotoshi Orimo, R. Postuma, S. Ramaswamy, O. Ross, D. Salmon, A. Singleton, Angela S. Taylor, Alan J. Thomas, P. Tiraboschi, J. Toledo, J. Trojanowski, D. Tsuang, Z. Walker, M. Yamada, K. Kosaka   +62 more
semanticscholar   +1 more source