A critical literature review exploring the challenges of delivering effective palliative care to older people with dementia in the acute hospital setting [PDF]
, 2008 Aim. This paper considers the challenges of delivering effective palliative care to older people with dementia and the possible strategies to overcome barriers to endof-life care in these patients. Background.
Birch, Deborah, Draper, Janet
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Activation of NMDA receptors in brain endothelial cells increases transcellular permeability
Fluids and Barriers of the CNS, 2022 Neurovascular coupling is a precise mechanism that induces increased blood flow to activated brain regions, thereby providing oxygen and glucose.
Kyu-Sung Kim +4 more
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Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study. [PDF]
, 2010 INTRODUCTION: Evidence from clinical samples and geographically limited population studies suggests that vascular health, diabetes and apolipoprotein epsilon4 (APOE) are associated with dementia. METHODS: A population-based sample of 856 individuals aged
Fisher, Gwenith G +8 more
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Impact of dementia: Health disparities, population trends, care interventions, and economic costs
Journal of The American Geriatrics Society, 2021 The dementia experience is not a monolithic phenomenon—and while core elements of dementia are considered universal—people living with dementia experience the disorder differently. Understanding the patterning of Alzheimer's disease and related dementias
M. Aranda +7 more
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Experimental and Molecular Medicine, 2020 Neurodegenerative disorders: Spread of misfolded protein aggregates Further research is needed to determine how an aggregate-forming protein common to several neurodegenerative disorders propagates throughout the brain.
Myungjin Jo +5 more
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BMC Psychiatry, 2023 Background The Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied on self-report or proxies for dementia such as cognitive tests. Our aims were twofold: a) to describe a
Donncha S. Mullin +15 more
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A systematic review and meta-analysis on the prevalence of dementia in europe. estimates from the highest-quality studies adopting the dsm iv diagnostic criteria [PDF]
, 2018 BACKGROUND: Dementia, including Alzheimer's disease (AD), is one of the most burdensome medical conditions. Usually, the reviews that aim at calculating the prevalence of dementia include estimates from studies without assessing their methodological ...
Bacigalupo, I +7 more
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Dementias show differential physiological responses to salient sounds
Frontiers in Behavioral Neuroscience, 2015 Abnormal responsiveness to salient sensory signals is often a prominent feature of dementia diseases, particularly the frontotemporal lobar degenerations, but has been little studied. Here we assessed processing of one important class of salient signals,
Phillip David Fletcher +10 more
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BMJ Open, 2021 Objectives The aim of this study was to establish the impact of dementia education and training on the knowledge, attitudes and confidence of health and social care staff.
Sahdia Parveen +6 more
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Through the eyes of others - The social experiences of people with dementia: A systematic literature review and synthesis [PDF]
, 2017 Psychosocial models suggest that the lived experience of dementia is affected by interpersonal factors such as the ways in which others view, talk about, and behave toward the person with dementia.
Clarke, Chris +7 more
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