Results 41 to 50 of about 509,561 (237)
Human iPSC-derived glia models for the study of neuroinflammation
Journal of Neuroinflammation, 2023 Neuroinflammation is a complex biological process that plays a significant role in various brain disorders. Microglia and astrocytes are the key cell types involved in inflammatory responses in the central nervous system.
Nina Stöberl +4 more
doaj +1 more source
Dementia in England: Quantifying and analysing modifiable risk [PDF]
arXiv, 2022 The prevalence of dementia is set to explode throughout the 21st century. This trend has already started in developed countries and will continue to place heavy pressures on both public health and social care services across the world. No cure for dementia is likely within the foreseeable future, however, medical research highlights the potential to ...
arxiv
A collective case study of the features of impactful dementia training for care home staff
BMC Geriatrics, 2019 Background Up to 80% of care home residents have dementia. Ensuring this workforce is appropriately trained is of international concern. Research indicates variable impact of training on a range of resident and staff outcomes. Little is still known about
Claire A. Surr +6 more
doaj +1 more source
BMC NeurologyBackground Dementia prevalence is predicted to triple to 152 million globally by 2050. Alzheimer’s disease (AD) constitutes 70% of cases. There is an urgent need to identify individuals with preclinical AD, a 10–20-year period of progressive brain ...
Jane Alty +20 more
doaj +1 more source
Towards Interpretability of Speech Pause in Dementia Detection using Adversarial Learning [PDF]
arXiv, 2021 Speech pause is an effective biomarker in dementia detection. Recent deep learning models have exploited speech pauses to achieve highly accurate dementia detection, but have not exploited the interpretability of speech pauses, i.e., what and how positions and lengths of speech pauses affect the result of dementia detection.
arxiv
Care partner experience with telepresence robots in long-term care during COVID-19 pandemic
Digital HealthObjective As people living with dementia move into long-term care (LTC), their care partners face a difficult role change from primary caregiver to visitor, losing a significant degree of control and direct care involvement.
Grace Hu +9 more
doaj +1 more source
Dementia Assessment Using Mandarin Speech with an Attention-based Speech Recognition Encoder [PDF]
arXiv, 2023 Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech recognition model to construct a dementia assessment system tailored for Mandarin speakers during the picture description ...
arxiv
Alzheimer’s disease-associated complement gene variants influence plasma complement protein levels
Journal of Neuroinflammation, 2023 Background Alzheimer’s disease (AD) has been associated with immune dysregulation in biomarker and genome-wide association studies (GWAS). GWAS hits include the genes encoding complement regulators clusterin (CLU) and complement receptor 1 (CR1 ...
Aurora Veteleanu +11 more
doaj +1 more source
Senile Dementia and Presenile Dementia
The Tohoku Journal of Experimental Medicine, 1990 Neurotransmitters including acetylcholine, dopamine, norepinephrine, serotonin, GABA and vasopressin were examined in control subjects and patients with Alzheimer-type dementia, involving presenile and senile dementia. Neurotransmitters exhibited various mode of changes with aging.
openaire +3 more sources
CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks
Nature CommunicationsDNA-protein interactions have traditionally been profiled via chromatin immunoprecipitation followed by next-generation sequencing (ChIP-seq). Cleavage Under Targets & Tagmentation (CUT&Tag) is a rapidly expanding technique that enables the profiling of ...
Leyla Abbasova +7 more
doaj +1 more source