Results 51 to 60 of about 509,561 (237)

The brain basis of musicophilia: evidence from frontotemporal lobar degeneration

open access: yesFrontiers in Psychology, 2013
Musicophilia, or abnormal craving for music, is a poorly understood phenomenon that has been associated in particular with focal degeneration of the temporal lobes.
Phillip David Fletcher   +3 more
doaj   +1 more source

Dementia ascertainment using existing data in UK longitudinal and cohort studies: a systematic review of methodology

open access: yesBMC Psychiatry, 2017
Background Studies investigating the risk factors for or causation of dementia must consider subjects prior to disease onset. To overcome the limitations of prospective studies and self-reported recall of information, the use of existing data is key ...
Ruth A. Sibbett   +3 more
doaj   +1 more source

Is later-life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post-mortem human brain tissue?

open access: yesAlzheimer’s Research & Therapy, 2023
Background Depression and dementia are both common diseases. Although new cases of depression are more common in younger adults, there is a second peak at the age of 50 years suggesting a different pathological process.
Lindsey I. Sinclair   +7 more
doaj   +1 more source

Memantine for dementia [PDF]

open access: yesCochrane Database of Systematic Reviews, 2006
Memantine is a moderate affinity uncompetitive antagonist of glutamate NMDA receptors. It is licensed for use in moderate and severe Alzheimer's disease (AD); in the USA, it is also widely used off-label for mild AD.To determine efficacy and safety of memantine for people with dementia. To assess whether memantine adds benefit for people already taking
Jennifer Ware   +8 more
openaire   +5 more sources

The barriers and facilitators to implementing dementia education and training in health and social care services: a mixed-methods study

open access: yesBMC Health Services Research, 2020
Background The health and social care workforce requires access to appropriate education and training to provide quality care for people with dementia. Success of a training programme depends on staff ability to put their learning into practice through ...
Claire A. Surr   +6 more
doaj   +1 more source

Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals

open access: yesAlzheimer’s Research & Therapy, 2021
Background To systematically examine the clinical utility of tau-PET and Braak-staging as prognostic markers of future cognitive decline in older adults with and without cognitive impairment.
Davina Biel   +7 more
doaj   +1 more source

Risk factors for dementia in the ninth decade of life and beyond: a study of the Lothian birth cohort 1921

open access: yesBMC Psychiatry, 2017
Background With increasing numbers of people surviving beyond eighty years, this section of the population demands attention to reduce the impact of dementia.
Ruth A. Sibbett   +3 more
doaj   +1 more source

The effect of a dementia awareness class on changing dementia attitudes in adolescents

open access: yesBMC Geriatrics, 2020
Background Current evidence suggests that negative and stigmatising attitudes towards dementia may develop at a young age. There are a number of dementia education and awareness initiatives aimed at reducing stigma, though they have not been robustly ...
Nicolas Farina   +6 more
doaj   +1 more source

A brain signature highly predictive of future progression to Alzheimer's dementia [PDF]

open access: yesarXiv, 2017
Early prognosis of Alzheimer's dementia is hard. Mild cognitive impairment (MCI) typically precedes Alzheimer's dementia, yet only a fraction of MCI individuals will progress to dementia, even when screened using biomarkers. We propose here to identify a subset of individuals who share a common brain signature highly predictive of oncoming dementia ...
arxiv  

Functional neuroanatomy of auditory scene analysis in Alzheimer's disease

open access: yesNeuroImage: Clinical, 2015
Auditory scene analysis is a demanding computational process that is performed automatically and efficiently by the healthy brain but vulnerable to the neurodegenerative pathology of Alzheimer's disease.
Hannah L. Golden   +7 more
doaj   +1 more source

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