Results 61 to 70 of about 1,350,087 (353)

Syntaphilin loss enhances mitochondrial axonal transport and neuromuscular junction formation in a human stem cell derived neuromuscular assembloid model

open access: yesMolecular Medicine
Background The neuromuscular junction (NMJ) is the synapse between motor neurons and skeletal muscle and controlls movement. Impaired synaptic transmission and NMJ degeneration has been observed during healthy ageing and is also implicated in several ...
Andrea Salzinger   +8 more
doaj   +1 more source

Medicines management issues in dementia and coping strategies used by people living with dementia and family carers: a systematic review [PDF]

open access: yes, 2018
Objectives: Medicines play a key role in the lives of people with dementia, primarily to manage symptoms. Managing medicines is complex for people with dementia and their family carers and can result in multiple problems leading to harm. We conducted a
Lim, Rosemary H., Sharmeen, Taniya
core   +1 more source

Diagnosis and Management of Dementia: Review.

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Worldwide, 47 million people live with dementia and, by 2050, the number is expected to increase to 131 million. Observations Dementia is an acquired loss of cognition in multiple cognitive domains sufficiently severe to affect social or ...
Z. Arvanitakis, R. Shah, D. Bennett
semanticscholar   +1 more source

Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

open access: yesDementia & Neuropsychologia, 2022
There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life.
Paulo Caramelli   +17 more
semanticscholar   +1 more source

Exploring the Relationship Between Deficits in Social Cognition and Neurodegenerative Dementia: A Systematic Review [PDF]

open access: gold, 2022
Esther Setién‐Suero   +5 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi   +8 more
wiley   +1 more source

Alzheimer's & Dementia: The Journal of the Alzheimer's Association

open access: yesAlzheimer's & Dementia, 2020
WethankDrs. Di Lorenzo andKoch for sharing their interest and views regarding our recent report on in vivo measurement of synaptic loss in Alzheimer’s disease (AD) using positron emission tomography (PET) to quantify [11C]UCB-J binding to synaptic ...
A. Mecca, Christopher H. Dyck
semanticscholar   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski   +13 more
wiley   +1 more source

Care partner experience with telepresence robots in long-term care during COVID-19 pandemic

open access: yesDigital Health
Objective As people living with dementia move into long-term care (LTC), their care partners face a difficult role change from primary caregiver to visitor, losing a significant degree of control and direct care involvement.
Grace Hu   +9 more
doaj   +1 more source

Developing Dementia-Friendly Tourism Destinations: An Exploratory Analysis [PDF]

open access: yes, 2014
Dementia is emerging as a global issue. Increases in life expectancy create an older population structure with accompanying health needs but also high lifestyle expectations.
Alzheimer’s Society   +32 more
core   +1 more source

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