Results 141 to 150 of about 2,546 (159)
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Improved HPLC Method for the Determination of Curcumin, Demethoxycurcumin, and Bisdemethoxycurcumin

Journal of Agricultural and Food Chemistry, 2002
Commercially available curcumin, a bright orange-yellow color pigment of turmeric, consists of a mixture of three curcuminoids, namely, curcumin, demethoxycurcumin, and bisdemethoxycurcumin. These were isolated by column chromatography and identified by spectroscopic studies. The purity of the curcuminoids was analyzed by an improved HPLC method.
Guddadarangavvanahally K, Jayaprakasha   +2 more
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Purification of Curcumin, Demethoxycurcumin, and Bisdemethoxycurcumin by High-Speed Countercurrent Chromatography

Journal of Agricultural and Food Chemistry, 2008
Curcuminoids are substances of great interest because of their important pharmacological activities, particularly anti-inflammatory, anticarcinogenic, and anti-Alzheimer's activities. In this study, we report the first procedure and effect of processing for the high, efficient, and useful purification of curcumin, demethoxycurcumin, and ...
Koichi, Inoue   +5 more
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ChemInform Abstract: Direct Synthesis of Demethoxycurcumin.

ChemInform, 1994
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Separation and determination of the physico-chemical characteristics of curcumin, demethoxycurcumin and bisdemethoxycurcumin

Food Research International, 2005
The objective of this work was to separate and determine the physico-chemical and color characteristics of isolated curcuminoid pigments. Thin-layer chromatographic separation of curcuminoid pigments was possible on silica gel 60G plates using dichloromethane:methanol, 99:1.
L. Péret-Almeida   +4 more
openaire   +1 more source

Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats

Psychopharmacology, 2014
Recent animal studies reported that curcumin, the active constituent of Curcuma longa, has several central actions and may attenuate morphine tolerance.In the present study, we utilized the intracranial self-stimulation (ICSS) paradigm to examine the effects of the commercially available curcuminoid mixture and each one of its components, individually,
Vicky, Katsidoni   +5 more
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Demethoxycurcumin: A naturally occurring curcumin analogue for treating non‐cancerous diseases

Journal of Cellular Physiology, 2019
AbstractTurmeric extracts contain three primary compounds, which are commonly referred to as curcuminoids. They are curcumin, demethoxycurcumin (DMC), and bisdemethoxycurcumin. While curcumin has been the most extensively studied of the curcuminoids, it suffers from low overall oral bioavailability due to extremely low absorption as a result of low ...
Mahdi Hatamipour   +4 more
openaire   +2 more sources

[Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009
To investigate the stability of curcumin, demethoxycurcumin and bisdemethoxycurcumin in different buffer solution.To determine concentration of curcumin by HPLC when added curcumin, demethoxycurcumin and bisdemethoxycurcumin into the buffer solution the equation of degradation was established.The sequence of stability are bisdemethoxycurcumin > or ...
Gang, Han   +4 more
openaire   +1 more source

Demethoxycurcumin suppresses HK2-mediated glycolysis by targeting PTEN/Akt signaling

Cancer Gene Therapy
Aerobic glycolysis is a hallmark of tumor cells, with the expression of glycolytic enzymes often being upregulated in many cancers, leading to enhanced metabolic activity. Among the key rate-limiting enzymes in this process, Hexokinase 2 (HK2) plays a crucial role in sustaining the biological activities of human cancers.
Jinzhuang Liao   +7 more
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Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators In Vitro and In Vivo

Archives of Pharmacal Research, 2008
Demethoxycurcumin and bisdemethoxycurcumin are the main active ingredients isolated from Curcumae Longae Radix. Recent studies demonstrated that both compounds exhibit antioxidative and anti-inflammatory effects as well as effects on cancer cell lines.
Lian Yu, Guo   +7 more
openaire   +2 more sources

[Study on pharmacokinetics of demethoxycurcumin phospholipid complex in rats].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015
To study the pharmacokinetics of Demethoxycurcumin phospholipid complex in rats with oral administration.Drawing blood from the SD rats after oral administration Demethoxycurcumin phospholipid complex and free demethoxycurcumin. The blood concentration were determined by HPLC.The pharmacokinetics parameter of Demethoxycurcumin phos- pholipid complex ...
Jian-chun, Luo   +4 more
openaire   +1 more source

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