Results 71 to 80 of about 2,546 (159)

Simultaneous determination of three curcuminoids in Curcuma longa L. by high performance liquid chromatography coupled with electrochemical detection

Journal of Pharmaceutical Analysis, 2014
A novel method for analysis of three active components curcumin, demethoxycurcumin and bisdemethoxycurcumin in Curcuma longa L. was developed by HPLC coupled with electrochemical detection.
Yuling Long, Wenpeng Zhang, Fang Wang, Zilin Chen   +3 more
doaj   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

BioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh, Vikas Sharma, Blessing Nnenna Udeh, Baisakhi Banerjee   +3 more
wiley   +1 more source

Demethoxycurcumin was prior to temozolomide on inhibiting proliferation and induced apoptosis of glioblastoma stem cells

Tumor Biology, 2015
Temozolomide (TMZ) is widely used for treating glioblastoma (GBM), which can effectively inhibit the GBM growth for some months; however, it still could not prevent the invariable recurrence of GBM. The existence of glioma stem cells (GSCs) was considered to be a key factor. But TMZ has poor effects on GSCs.
Lei, Shi, Xifeng, Fei, Zhimin, Wang
openaire   +2 more sources

Peptic Ulcer Disease Treatment Using Herbal Plants: Harnessing Ethnobotanical Studies for Clinical Application

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Peptic ulcer disease (PUD) is a major gastrointestinal disorder associated with Helicobacter pylori (H. pylori) infection, nonsteroidal anti‐inflammatory drug (NSAID) use, and impaired mucosal defense. Ethnobotanical studies have revealed that the heavy reliance on medicinal plants as a treatment option for ulcers is usually guided by ...
Emmanuel Okoampah, Joseph Payne, Joan Davids Shine, Philomina Agyeman, Princess Ofosuhemaa, Osman A. Dufailu, Faisal Raza   +6 more
wiley   +1 more source

Anti-Inflammatory, Wound Healing, and Anti-Diabetic Effects of Pure Active Compounds Present in the Ryudai Gold Variety of Curcuma longa

Molecules
Turmeric (Curcuma longa) contains curcumin, demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC). Nevertheless, curcumin is the most researched active ingredient for its numerous pharmacological effects.
Md Zahorul Islam, Jesmin Akter, Md Amzad Hossain, Md Shafiqul Islam, Purba Islam, Chayon Goswami, Ha Thi Thanh Nguyen, Atsushi Miyamoto   +7 more
doaj   +1 more source

Fluorescent properties of chitosan-stabilized bisdemethoxycurcumin-silver nanoparticles: Synthesis and characterization

Results in Chemistry
The extraction and modification of naturally-occurring compounds are widely performed due to their valuable medicinal and physical properties. Herin, we reported the extraction of bis-demethoxycurcumin from Ragbrai turmeric root.
Shayma M. Ahmad, Farah M. Ibrahim, Amer Adnan Hasan, Haitham Mawlood Mikhlif, Rasha Saad Jwad, Zamzam Alhuwaymil, Sohad A. Alshareef, Mohammed S.S. Alyami, Mohammed H. Al-Mashhadani, Srikanth Kommanaboyina   +9 more
doaj   +1 more source

Production of in Different Organs of

Natural Product Communications, 2012
Curcuma longa L. (turmeric) is one of the most important spice and safe food additives. Its main constituents, curcuminoids, showed anti-inflammatory, antitumor and antioxidant effects. In the present work, an in vitro propagation method was developed to
Laura Pistelli, Alessandra Bertoli, Federica Gelli, Laura Bedini, Barbara Ruffoni, Luisa Pistelli   +5 more
doaj   +1 more source

Exploring the therapeutic potential of demethoxycurcumin in periodontitis

Abstract Objectives This computational analysis investigated the potential benefits of Demethoxycurcumin (DMC) and studied the antimicrobial ligand binding sites of DMC specifically in the key endotoxin, Lipid A of P.gingivalis and host modulation with chemokine receptor of oral fibroblasts (CCR3/CCR4). Materials and Methods Protein structure
Saravanan Sampoornam Pape Reddy, Delfin Lovelina Francis, Harshini Thirumoorthi, Devendra Srivast, Neelima Katti, Sukhbir Singh Chopra   +5 more
openaire   +1 more source

Effects of Three Kinds of Curcuminoids on Anti-Oxidative System and Membrane Deformation of Human Peripheral Blood Erythrocytes in High Glucose Levels

Cellular Physiology and Biochemistry, 2015
Background/Aims: Curcuminoids are the main bioactive constituents of the rhizome of turmeric. Erythrocytes lesions in diabetes are probably related to hyperglycemia and protein glycation.
Wei Yang, Juan Fu, Miao Yu, Di Wang, Ying Rong, Ping Yao, Andreas K. Nüssler, Hong Yan, Liegang Liu   +8 more
doaj   +1 more source

Determination of antiplasmodial activity and binding affinity of curcumin and demethoxycurcumin towardsPfTrxR

Natural Product Research, 2014
In our study, the inhibitory activity of curcuminoids towards Plasmodium falciparum thioredoxin reductase (PfTrxR) was determined using LC-MS-based functional assay and showed that only demethoxycurcumin (DMC) inhibited PfTrxR (IC50: 2 μM). In silico molecular modelling was used to ascertain and further confirm that the binding affinities of curcumin ...
Ranjith, Munigunti, Symon, Gathiaka, Orlando, Acevedo, Rajnish, Sahu, Babu, Tekwani, Angela I, Calderón   +5 more
openaire   +2 more sources