Results 231 to 240 of about 25,929 (279)

Targeting epigenetic regulators to boost T cell immunotherapy against cancer. [PDF]

Cell Biosci
Xiao T, Zhang YE.
europepmc   +1 more source

Methyl-Lysine-Dependent Control of Protein Lifetime Through Lysine-Node Crosstalk and Reader-Coupled Degradation. [PDF]

Biology (Basel)
Morrison BE.
europepmc   +1 more source

Epigenetic crossroads in intervertebral disc degeneration: Unlocking novel therapeutic avenues (Review). [PDF]

Mol Med Rep
Hou Y, Liu L, Guo Y, Shi J.
europepmc   +1 more source

Role and mechanisms of m6A demethylases in digestive system tumors. [PDF]

Am J Cancer Res
Jiang L, Chen Y, Luo Q, Song G.
europepmc   +1 more source

The emerging role of m⁶A methylation in prostate-related diseases: mechanisms and clinical implications. [PDF]

Front Immunol
Xie Q, Zhao H, Yang X, Zhang H, Liu H, Pan J, Li Y, Fan D, Fan X.   +8 more
europepmc   +1 more source

The role of histone demethylases in cancer therapy

Molecular Oncology, 2012
Reversible histone methylation has emerged in the last few years as an important mechanism of epigenetic regulation. Histone methyltransferases and demethylases have been identified as contributing factors in the development of several diseases ...
Martin Roatsch, Martin Pippel, Wolfgang Sippl   +2 more
exaly   +2 more sources

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When Is a Demethylase Not a Demethylase?

Science Signaling, 2011
The histone lysine demethylase JARID1a has demethylase-independent function in the circadian clock.
openaire   +2 more sources

Lysine-Specific Histone Demethylases Contribute to Cellular Differentiation and Carcinogenesis

Epigenomes, 2017
Histone modifications regulate chromatin structure, gene transcription, and other nuclear processes. Among the histone modifications, methylation has been considered to be a stable, irreversible process due to the slow turnover of methyl groups in ...
Gaetano Verdé, Sandra Peiro
exaly   +2 more sources