Results 11 to 20 of about 13,046 (101)
Trifluoromethylation of Carbonyl and Unactivated Olefin Derivatives by C(sp3)−C Bond Cleavage
Angewandte Chemie, Volume 135, Issue 15, April 3, 2023., 2023 A Cu‐mediated trifluoromethylation of carbonyl‐type compounds and unactivated olefins enabled by visible‐light irradiation via σ C(sp3)−C bond‐functionalization has been developed. This protocol is characterized by its modularity, mild conditions and wide scope—even in the context of late‐stage functionalization, thus offering a complementary approach ...
Fei Cong +4 more
wiley +2 more sources
Angewandte Chemie, Volume 135, Issue 8, February 13, 2023., 2023 Herein, we describe the development of a copper‐catalyzed C(sp3)‐amination of proaromatic dihydroquinazolinones derived from ketone building blocks. The reaction is enabled by the intermediacy of open‐shell species arising from homolytic C−C bond‐cleavage driven by aromatization.
Xin‐Yang Lv +2 more
wiley +2 more sources
Reversible Isomerization Between Silacyclopropyl Cation and Cyclic (Alkyl)(Amino)Silylene
Angewandte Chemie, Volume 135, Issue 4, January 23, 2023., 2023 A phosphine‐stabilized silacyclopropyl cation has been synthesized and fully characterized. Interestingly, this silacyclopropyl cation reversibly isomerizes into the corresponding seven‐membered cyclic (alkyl)(amino)silylene at room temperature via a formal migratory ethylene insertion into the Si−P bond.
Raphaël Nougué +5 more
wiley +2 more sources
Transition‐Metal‐Catalyzed Annulations Involving the Activation of C(sp3)−H Bonds
Angewandte Chemie, Volume 134, Issue 6, February 1, 2022., 2022 The number of methods that exploit transition‐metal‐catalyzed C(sp3)−H activations for the assembly of cyclic systems is steadily growing. This Minireview covers the most relevant cyclization and cycloaddition approaches, discussed from a mechanistic perspective.
Marc Font +2 more
wiley +2 more sources
An Innovative Approach for the Generation of Species of the Interstellar Medium
Angewandte Chemie, Volume 133, Issue 46, Page 24666-24671, November 8, 2021., 2021 Laser ablation of solid organic compounds with high melting points is proposed for the in situ generation of new chemical species. Diaminomaleonitrile is used as a prototypical precursor, generating numerous interstellar compounds and aminocyanoacetylene for the first time.
Lucie Kolesniková +4 more
wiley +2 more sources
Angewandte Chemie, Volume 133, Issue 40, Page 22188-22196, September 27, 2021., 2021 This work demonstrates that catalytic processes involving metal–carbene intermediates can be exported to the crowded magma of a live mammalian cell. In particular, reactions involving copper carbenes can be used for the synthesis of fluorescent cyclic products in cellular media, in a process that is initiated by an N−H carbene insertion.
Sara Gutiérrez +2 more
wiley +2 more sources
Bioorthogonal Azide–Thioalkyne Cycloaddition Catalyzed by Photoactivatable Ruthenium(II) Complexes
Angewandte Chemie, Volume 133, Issue 29, Page 16195-16202, July 12, 2021., 2021 Tailored cationic RuII complexes are highly effective precatalysts for ruthenium‐catalyzed azide–thioalkyne cycloaddition (see scheme). These reactions can now be carried out under very dilute conditions and in complex biorelevant media; they are also compatible with and mutually orthogonal to CuAAC.
Alejandro Gutiérrez‐González +5 more
wiley +2 more sources
Chemistry – A European Journal, Volume 28, Issue 70, December 15, 2022., 2022 Various base‐stabilized silyliumylidene ions with different ligands were synthesized. Their behaviour appeared strongly dependent on the type of ligand. Indeed, in contrast to the poorly reactive silyliumylidenes stabilized by strongly donating ligands (DMAP, NHC), the sulfide‐supported one (SMe2) exhibits higher reactivity toward various small ...
Raphaël Nougué +7 more
wiley +1 more source
An Expedient Method for the Umpolung Coupling of Enols with Heteronucleophiles**
Chemistry – A European Journal, Volume 28, Issue 44, August 4, 2022., 2022 A useful strategy: Herein, we report an umpolung strategy mediated by a hypervalent iodine(III) reagent for the functionalization of enol derivatives with different heteronucleophiles including carboxylic acids, thiols, alcohols, primary and secondary amines, azides and carbamates generated from CO2.
Víctor García‐Vázquez +4 more
wiley +1 more source
Chemistry – A European Journal, Volume 27, Issue 53, Page 13352-13357, September 20, 2021., 2021 It's a match! A novel shape‐persistent chiral cage constituting two N‐heterotriangulene lids and three bis(diethynylallene) branches is reported, along with UV/vis complexation studies with both charged and neutral helicenes. Enantioselective discrimination was observed, which, in combination with the redox behavior of the host, makes the system ...
Sandra Míguez‐Lago +3 more
wiley +1 more source