Results 1 to 10 of about 50 (48)
Demyelination in rheumatic diseases [PDF]
Postgraduate Medical Journal, 2008 Abstract Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterised by multifocal areas of demyelination in the white matter of the brain and spinal cord. Autoantibodies, for example antinuclear antibodies, can also be present.
A Theodoridou, Loukas Settas
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Macrophages and Autoantibodies in Demyelinating Diseases [PDF]
Cells, 2021 Myelin phagocytosis by macrophages has been an essential feature of demyelinating diseases in the central and peripheral nervous systems, including Guillain–Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and multiple sclerosis (MS). The discovery of autoantibodies, including anti-ganglioside GM1 antibodies in the axonal
Haruki Koike, Masahisa Katsuno
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Atypical demyelinating disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1974 A 17 year old girl died after an illness characterized by progressive mental deterioration and severe myoclonic jerks. Extensive pathological, virological, and immunological studies failed to support the diagnosis of subacute sclerosing panencephalitis but were compatible with disseminated demyelinating disease.
J. M. Adams +5 more
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Journal of Clinical Pathology, 2006 A diagnosis of demyelination carries important therapeutic and prognostic implications. In most cases the diagnosis is made clinically, and involvement of the histopathologist is largely confined to postmortem confirmation and clinicopathological correlation.
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Fulminant Demyelinating Diseases [PDF]
The Neurohospitalist, 2013 Fulminant demyelinating disease is a heading that covers acute disseminated encephalomyelitis and its variant acute hemorrhagic leukoencephalitis (Hurst disease), severe relapses of multiple sclerosis (MS), variants of MS (tumefactive MS, Marburg variant, Balo concentric sclerosis, myelinoclastic diffuse sclerosis), and neuromyelitis optica-spectrum ...
Orhun H. Kantarci, Megan R. Rahmlow
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Anaesthesia and demyelinating disease [PDF]
Anaesthesia, 1980 SummaryThe demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and techniques are discussed.
T. E. J. Healy, Ronald M. Jones
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Cell therapy in demyelinating diseases [PDF]
Neurotherapeutics, 2004 Multiple sclerosis presents particular and serious problems to those attempting to develop cell-based therapies: the occurrence of innumerable lesions scattered throughout the CNS, axon loss, astrocytosis, and a continuing inflammatory process, to name but a few.
CA Halfpenny +3 more
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Glial grafting for demyelinating disease [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2005 Remyelination of demyelinated central nervous system (CNS) axons is considered as a potential treatment for multiple sclerosis, and it has been achieved in experimental models of demyelination by transplantation of pro-myelinating cells. However, the experiments undertaken have not addressed the need for tissue-type matching in order to achieve graft ...
W. F. Blakemore, Vanja Tepavcevic
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The virology of demyelinating diseases [PDF]
Annals of Neurology, 1994 Infectious agents have been postulated as causes of multiple sclerosis for over a century. The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and "viral" infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections in humans can cause diseases with
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Neuroradiological evaluation of demyelinating disease [PDF]
Therapeutic Advances in Neurological Disorders, 2013 Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging criteria.
Jan Mendelt Tillema, Istvan Pirko
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