Results 11 to 20 of about 70,385 (287)

Reactivity to Novel Autoantigens in Patients with Coexisting Central Nervous System Demyelinating Disease and Autoimmune Thyroid Disease [PDF]

Frontiers in Immunology, 2017
Several lines of evidence suggest a definite and unique link between CNS demyelinating diseases and autoimmune thyroid disease (AITD). The aim of the current study was to systematically compare the clinical and laboratory features of patients with ...
Judith M. Greer, Simon Broadley, Simon Broadley, Michael P. Pender, Michael P. Pender   +4 more
doaj   +3 more sources

Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease

Neural Regeneration Research, 2023
Schwann cells, the myelinating glia of the peripheral nervous system, wrap axons multiple times to build their myelin sheath. Myelin is of paramount importance for axonal integrity and fast axon potential propagation.
Nadège Hertzog, Claire Jacob
doaj   +2 more sources

Effects of Keratinocyte-Derived Cytokine (CXCL-1) on the Development of Theiler's Virus-Induced Demyelinating Disease

Frontiers in Cellular and Infection Microbiology, 2018
CXCL-1, also called keratinocyte-derived cytokine (KC), is a predominant chemokine produced in glial cells upon infection with Theiler's murine encephalomyelitis virus (TMEV).
Min H. Kang, Young H. Jin, Byung S. Kim
doaj   +2 more sources

Demyelinating neuropathy as the initial presentation of familial E200K Creutzfeldt–Jakob disease in two patients

Annals of Clinical and Translational Neurology
Objective To describe peripheral neuropathy associated with familial Creutzfeldt‐Jakob disease. Methods We report two unrelated patients with genetic Creutzfeldt–Jakob disease with demyelinating peripheral neuropathy as initial presentation, with a ...
Cécile Delorme, Antoine Pégat, Julian Theuriet, Jean‐Philippe Brandel, Emmanuel Roze, Karine Viala, Julie Zyss, Stéphane Thobois, Anthony Fourier, Emilien Bernard, Juliette Svahn, Chloé Laurencin, Paul Jaulent, Christophe Vandendries, Isabelle Quadrio, Virginie Desestret, David Meyronet, Thierry Maisonobe, Stéphane Haïk, Danielle Seilhean   +19 more
doaj   +2 more sources

Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab

Journal for ImmunoTherapy of Cancer, 2018
Background Ipilimumab is an FDA-approved anti-CTLA-4 monoclonal antibody used in treatment of metastatic melanoma. We present an unusual neurological complication of Ipilimumab therapy and the diagnostic dilemma it caused. Case presentation A 42 year old
Lorraine Cafuir, David Lawson, Nilesh Desai, Vita Kesner, Alfredo Voloschin   +4 more
doaj   +2 more sources

Demyelinating disease masquerading as a surgical problem: a case series

Journal of Medical Case Reports, 2009
Introduction We report three cases of demyelinating disease with tumor-like presentation. This information is particularly important to both neurosurgeons and neurologists who should be aware that inflammatory demyelinating diseases can present as a mass
Awang Saufi M, Saiful Nayan M, Madhavan Mohan, Abdullah Jafri, Tharakan John K   +4 more
doaj   +2 more sources

Glutamate Receptors in Neuroinflammatory Demyelinating Disease [PDF]

Mediators of Inflammation, 2006
Multiple sclerosis (MS) is a chronic demyelinating disease of the human central nervous system (CNS). The condition predominantly affects young adults and is characterised by immunological and inflammatory changes in the periphery and CNS that contribute
Christopher Bolton, Carolyn Paul
doaj   +3 more sources

Refractory Celiac Disease Causing Cavitating Mesenteric Lymph Node Syndrome and Celiac Disease Associated Central Nervous System Demyelinating Disorder

Gastro Hep Advances
Refractory celiac disease is a rare complex autoimmune-mediated disorder, which has multiple complications, among the best known is enteropathy-associated T-cell lymphoma, other rare complications are central nervous system demyelinating disorder and ...
Teresa Del Rio, MD, Blaire Burman, Asma Siddique, Erin Forsythe   +3 more
doaj   +2 more sources

Acute paretic syndrome in juvenile White Leghorn chickens resembles late stages of acute inflammatory demyelinating polyneuropathies in humans [PDF]

, 2010
Background: Sudden limb paresis is a common problem in White Leghorn flocks, affecting about 1% of the chicken population before achievement of sexual maturity.
Sascha Trapp, Bader, Sophie R., Hans-Christian Philipp, Kaspers, Bernd, Bader, Sophie R, Steffen Weigend, Sharifi, Ahmad R, Philipp, Hans-Christian, Trapp, Sascha, Sonja Kothlow, Weigend, Steffen, Sharifi, Ahmad R., Matiasek, Kaspar, Susanne CN Schwarz, Schmahl, Wolfgang W., Bernd Kaspers, Schwarz, Susanne C.N., Kothlow, Sonja, Sharifi, Ahmad Reza, Schwarz, Susanne C. N., Preisinger, Rudolf, Ahmad R Sharifi, Wolfgang Schmahl, Sophie R Bader, Kaspar Matiasek, Schmahl, Wolfgang, Rudolf Preisinger   +26 more
core   +1 more source

Virus demyelination [PDF]

, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source