Results 141 to 150 of about 67,279 (165)
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Proteinases in inflammatory demyelinating disease
Springer Seminars in Immunopathology, 1985Proteinases are likely to be involved in the generation of the immune response and the tissue injury found in inflammatory demyelination of the CNS and PNS. The mechanisms whereby proteinases effect changes in these disorders are imprecisely understood but may be important in terms of understanding susceptibility, the extent of tissue damage, and ...
Christopher T. Bever, John N. Whitaker
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Acute and Chronic Demyelinating Disease
Otolaryngologic Clinics of North America, 1987There are multiple entities subsumed under this title that have in common the primary destruction of central nervous system myelin with relative sparing of axons. The hereditary diseases are often referred to as dysmyelinating diseases in which there is a genetic defect in the formation or maintenance of myelin; they usually occur in children.
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Role of interferons in demyelinating diseases
1997IFN beta-1b reduces the frequency of major multiple sclerosis attacks by 50 percent. Serial MRI scanning over the course of the clinical trial that led to approval of the agent revealed a significant lessening both in disease activity and in accumulating burden of disease in IFN beta-1b-treated patients compared to placebo-treated controls.
Amit Dayal +4 more
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Cytokines in Demyelinating Diseases
2008Abstract Among the autoimmune diseases, multiple sclerosis (MS) has been up to now best understood with regard to the pathogenesis of inflammation and demyelination, which affects the white matter of the brain. In MS brain are founded focal infiltrates of T cells and macrophages, axonal injury, and loss of neurological functions 1 , 2 , 3 .
Natalia M. Kalinina +1 more
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PATHOPHYSIOLOGY OF DEMYELINATING DISEASE [PDF]
British Medical Bulletin, 1977 A M Halliday, W I McDonald
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