Results 11 to 20 of about 9,406,168 (354)

Central nervous system Cryptococcoma mimicking demyelinating disease: a case report

BMC Neurology, 2020
Background Cerebral cryptococcomas is a rare form of central nervous system cryptococcosis. Most previous cases were mistaken for neoplasm before surgery.
Jie Wei, Xiang-Yu Li, Yue Zhang
doaj   +2 more sources

Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease. [PDF]

PLoS ONE, 2017
Infection of various cells with Theiler's murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon ...
Seung Jae Kim, Young-Hee Jin, Byung S Kim   +2 more
doaj   +2 more sources

Neuroradiological evaluation of demyelinating disease

Therapeutic Advances in Neurological Disorders, 2013
Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging ...
Jan-Mendelt Tillema, Istvan Pirko
doaj   +2 more sources

Exosomal Circular RNA as a Biomarker Platform for the Early Diagnosis of Immune-Mediated Demyelinating Disease

Frontiers in Genetics, 2019
Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.
Jinting He, Ming Ren, Ming Ren, Haiqi Li, Le Yang, Xiaofeng Wang, Qiwei Yang   +6 more
doaj   +2 more sources

Akt3-Mediated Protection Against Inflammatory Demyelinating Disease

Frontiers in Immunology, 2019
Akt is a serine/threonine protein kinase that plays a major role in regulating multiple cellular processes. While the isoforms Akt1 and Akt2 are involved in apoptosis and insulin signaling, respectively, the role for Akt3 remains uncertain.
Juwen C. DuBois, Alex K. Ray, Ross C. Gruber, Yongwei Zhang, Ranee Aflakpui, Fernando Macian-Juan, Bridget Shafit-Zagardo   +6 more
doaj   +2 more sources

IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease

Journal of Neuroinflammation, 2012
Background Theiler’s virus infection induces chronic demyelinating disease in mice and has been investigated as an infectious model for multiple sclerosis (MS).
Kim Byung S, Jin Young-Hee, Meng Liping, Hou Wanqiu, Kang Hyun, Park Hey, Koh Chang-Sung   +6 more
doaj   +2 more sources

IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler's Murine Encephalomyelitis Viruses. [PDF]

Front Immunol, 2022
Bühler M, Runft S, Li D, Götting J, Detje CN, Nippold V, Stoff M, Beineke A, Schulz T, Kalinke U, Baumgärtner W, Gerhauser I.   +11 more
europepmc   +2 more sources

First case of SARS-COV-2 sequencing in cerebrospinal fluid of a patient with suspected demyelinating disease

Journal of Neurology, 2020
The association between coronaviruses and central nervous system (CNS) demyelinating lesions has been previously shown. However, no case has been described of an association between the novel coronavirus (SARS-COV-2) and CNS demyelinating disease so far.
R. Domingues, M. Mendes-Correa, Fernando Brunale Vilela de Moura Leite, E. Sabino, D. Salarini, I. Claro, D. W. Santos, J. D. de Jesus, N. E. Ferreira, C. Romano, C. S. Soares   +10 more
semanticscholar   +1 more source

The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody

Acta Neuropathologica, 2020
We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG) antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort.
R. Höftberger, Yong Guo, E. Flanagan, A. S. Lopez-Chiriboga, V. Endmayr, S. Hochmeister, Damir Joldic, Sean J. Pittock, J. Tillema, M. Gorman, H. Lassmann, Claudia F. Lucchinetti   +11 more
semanticscholar   +1 more source

The Clinical, Radiologic, and Prognostic Differences Between Pediatric and Adult Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Encephalomyelitis

Frontiers in Neurology, 2021
Purpose: To evaluate the clinical differences between pediatric and adult patients with myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (MOG-EM).Methods: We retrospectively reviewed the clinical features of pediatric and adult ...
Jie Xu, Jie Xu, Lingjuan Liu, Lingjuan Liu, Jie Xiong, Jie Xiong, Lu Zhang, Lu Zhang, Peng Huang, Peng Huang, Li Tang, Li Tang, Yangyang Xiao, Yangyang Xiao, Xingfang Li, Xingfang Li, Jian Li, Jian Li, Yingying Luo, Huiling Li, Dingan Mao, Dingan Mao, Liqun Liu, Liqun Liu   +23 more
doaj   +1 more source